Evidence map›Paper›PMID 35652093›Full record

ArticleFrontiers in cell and developmental biology2022

The ShGlom

Marie-Christin Ristov, Tim Lange, Nadine Artelt, Neetika Nath, Andreas W Kuss, Jochen Gehrig, Maja Lindenmeyer, Clemens D Cohen, Sheraz Gul, Karlhans Endlich and 2 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cell and developmental biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.9field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 1 country.

Marie-Christin RistovInstitute of Anatomy and Cell Biology, University Medicine Greifswald, Greifswald, Germany.
Tim LangeInstitute of Anatomy and Cell Biology, University Medicine Greifswald, Greifswald, Germany.
Nadine ArteltInstitute of Anatomy and Cell Biology, University Medicine Greifswald, Greifswald, Germany.
Neetika NathInstitute of Bioinformatics, University Medicine Greifswald, Greifswald, Germany.
Andreas W KussDepartment of Functional Genomics, Interfaculty Institute for Genetics and Functional Genomics, University of Greifswald, Greifswald, Germany.
Jochen GehrigAcquifer Imaging GmbH, Heidelberg, Germany.
Maja LindenmeyerIII Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Clemens D CohenNephrological Center, Medical Clinic and Policlinic IV, University of Munich, Munich, Germany.
Sheraz GulFraunhofer Institute for Translational Medicine and Pharmacology, Fraunhofer Cluster of Excellence Immune-Mediated Diseases CIMD, Hamburg, Germany.
Karlhans EndlichInstitute of Anatomy and Cell Biology, University Medicine Greifswald, Greifswald, Germany.
Uwe VölkerDepartment of Functional Genomics, Interfaculty Institute for Genetics and Functional Genomics, University of Greifswald, Greifswald, Germany.
Nicole EndlichInstitute of Anatomy and Cell Biology, University Medicine Greifswald, Greifswald, Germany.
Universitätsmedizin Greifswald · DEUniversität Greifswald · DEFraunhofer Institute for Translational Medicine and Pharmacology · DELudwig-Maximilians-Universität München · DEUniversity Medical Center Hamburg-Eppendorf · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chronic kidney disease (CKD) is a major public health burden affecting more than 500 million people worldwide. Podocytopathies are the main cause for the majority of CKD cases due to pathogenic morphological as well as molecular biological alterations of postmitotic podocytes. Podocyte de-differentiation is associated with foot process effacement subsequently leading to proteinuria. Since currently no curative drugs are available, high throughput screening methods using a small number of animals are a promising and essential tool to identify potential drugs against CKD in the near future. Our study presents the implementation of the already established mouse Glom

Indexed as

CKD—chronic kidney diseasecompounddifferentiationglomeruluspodocytescreeningvitamin D3

Identifiers

PMID35652093
PMCPMC9150175
OpenAlexW4280648786

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.