Evidence map›Paper›PMID 35652047›Full record

ArticleFrontiers in pharmacology2022

Fisetin: An Integrated Approach to Identify a Strategy Promoting Osteogenesis.

Luca Dalle Carbonare, Jessica Bertacco, Salvatore Calogero Gaglio, Arianna Minoia, Mattia Cominacini, Samuele Cheri, Michela Deiana, Giulia Marchetto, Anna Bisognin, Alberto Gandini and 4 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in pharmacology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

  1. Pooled it
  2. Cellular senescence and aging: molecular mechanisms and convergent pathways.Cellular and molecular life sciences : CMLS · 2026
    Review
  3. Review
  4. Article
  5. Review
  6. PEG-NHInternational journal of nanomedicine · 2026
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 1 institution in 1 country.

Luca Dalle CarbonareDepartment of Medicine, University of Verona, Verona, Italy.
Jessica BertaccoDepartment of Medicine, University of Verona, Verona, Italy.
Salvatore Calogero GaglioBiocrystallography Lab, Department of Biotechnology, University of Verona, Verona, Italy.
Arianna MinoiaDepartment of Medicine, University of Verona, Verona, Italy.
Mattia CominaciniDepartment of Medicine, University of Verona, Verona, Italy.
Samuele CheriDepartment of Medicine, University of Verona, Verona, Italy.
Michela DeianaDepartment of Medicine, University of Verona, Verona, Italy.
Giulia MarchettoDepartment of Medicine, University of Verona, Verona, Italy.
Anna BisogninBiocrystallography Lab, Department of Biotechnology, University of Verona, Verona, Italy.
Alberto GandiniDepartment of Surgery, Dentistry, Pediatrics and Gynecology, University of Verona, Verona, Italy.
Franco AntoniazziDepartment of Surgery, Dentistry, Pediatrics and Gynecology, University of Verona, Verona, Italy.
Massimiliano PerducaBiocrystallography Lab, Department of Biotechnology, University of Verona, Verona, Italy.
Monica MottesDepartment of Neurosciences, Biomedicine and Movement Sciences, University of Verona, Verona, Italy.
Maria Teresa ValentiDepartment of Medicine, University of Verona, Verona, Italy.
University of Verona · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Flavonoids may modulate the bone formation process. Among flavonoids, fisetin is known to counteract tumor growth, osteoarthritis, and rheumatoid arthritis. In addition, fisetin prevents inflammation-induced bone loss. In order to evaluate its favorable use in osteogenesis, we assayed fisetin supplementation in both

Indexed as

differentiationfisetinmesenchymal stem cellsosteogenesisPLGA

Identifiers

PMID35652047
PMCPMC9149166
OpenAlexW4280620134

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.