Evidence map›Paper›PMID 35651944›Full record

ArticleFrontiers in genetics2022

Meckel's Cartilage in Mandibular Development and Dysmorphogenesis.

M Kathleen Pitirri, Emily L Durham, Natalie A Romano, Jacob I Santos, Abigail P Coupe, Hao Zheng, Danny Z Chen, Kazuhiko Kawasaki, Ethylin Wang Jabs, Joan T Richtsmeier and 2 more

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Frontiers in genetics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03025763 (Craniosynostosis Network), which is not on this map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
3.7field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03025763 active not recruitingnot on this map

Craniosynostosis Network

TypeobservationalSponsorIcahn School of Medicine at Mount SinaiRan2015 to 2028Enrolled2,145ConditionsCraniosynostosisArmsCraniosynostosis Network Environmental Survey, 2D/3D Photography, Buccal Swab Cell Sampling, Blood sampling, Skin Biopsy
3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Embryonic cranial cartilage defects in the Fgfr3Anatomical record (Hoboken, N.J. : 2007) · 2025
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. The Contribution of Meckel's Cartilage-Derived Type II Collagen-Positive Cells to the Jawbone Development and Repair.The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society · 2024
    Article
  10. CONUNETR: A CONDITIONAL TRANSFORMER NETWORK FOR 3D MICRO-CT EMBRYONIC CARTILAGE SEGMENTATION.Proceedings. IEEE International Symposium on Biomedical Imaging · 2024
    Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

M Kathleen PitirriDepartment of Anthropology, The Pennsylvania State University, University Park, PA, United States.
Emily L DurhamDepartment of Anthropology, The Pennsylvania State University, University Park, PA, United States.
Natalie A RomanoDepartment of Anthropology, The Pennsylvania State University, University Park, PA, United States.
Jacob I SantosDepartment of Anthropology, The Pennsylvania State University, University Park, PA, United States.
Abigail P CoupeDepartment of Anthropology, The Pennsylvania State University, University Park, PA, United States.
Hao ZhengDepartment of Computer Science and Engineering, University of Notre Dame, Notre Dame, IN, United States.
Danny Z ChenDepartment of Computer Science and Engineering, University of Notre Dame, Notre Dame, IN, United States.
Kazuhiko KawasakiDepartment of Anthropology, The Pennsylvania State University, University Park, PA, United States.
Ethylin Wang JabsDepartment of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, United States.
Joan T RichtsmeierDepartment of Anthropology, The Pennsylvania State University, University Park, PA, United States.
Meng WuDepartment of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, United States.
Susan M Motch PerrineDepartment of Anthropology, The Pennsylvania State University, University Park, PA, United States.
Pennsylvania State University · USIcahn School of Medicine at Mount Sinai · USUniversity of Notre Dame · US

Funding

Project III: Systems Biology of Bone in Coronal Nonsyndromic CraniosynostosisP01HD078233 · NICHD · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI DREW, PATRICK JAMES, JABS, ETHYLIN WANG · 2014 to 2019
$7.0M
Transcriptome and Network Analysis of Cleft PalateR01DE029322 · NIDCR · MAYO CLINIC ROCHESTER · PI JABS, ETHYLIN WANG, VAN BAKEL, HARM · 2020 to 2024
$3.9M
Cartilage and bone of the lower jaw in development and diseaseR01DE031439 · NIDCR · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI Ethylin Wang Jabs, Kazuhiko Kawasaki · 2022 to 2026
$3.8M
Genetic, Tissue, and Anatomical Interactions in Mandibulofacial DysmorphogenesisR01DE029832 · NIDCR · MAYO CLINIC ROCHESTER · PI JABS, ETHYLIN WANG, KAWASAKI, KAZUHIKO · 2021 to 2024
$2.9M
The chondrocranium in craniofacial development and diseaseR01DE027677 · NIDCR · PENNSYLVANIA STATE UNIVERSITY, THE · PI RICHTSMEIER, JOAN THERESE · 2018 to 2022
$2.6M
NICHD NIH HHS P01 HD078233NIDCR NIH HHS R01 DE027677NIDCR NIH HHS R01 DE029322NIDCR NIH HHS R01 DE029832NIDCR NIH HHS R01 DE031439
6 · The paper itself

Abstract

The

Indexed as

craniofacial developmentCrouzon syndromeembryonic boneembryonic cartilagefibroblast growth factorlower jawmandibleskull

Identifiers

PMID35651944
PMCPMC9149363
OpenAlexW4280536458

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.