Evidence map›Paper›PMID 35651878›Full record

ArticleTransplant international : official journal of the European Society for Organ Transplantation2022

The MUC5B Promoter Polymorphism is Not Associated With Non-ILD Chronic Respiratory Diseases or Post-transplant Outcome.

Tinne Goos, Stijn E Verleden, Laurens J De Sadeleer, Anke Van Herck, Annelore Sacreas, Arno Vanstapel, Janne Kaes, Vincent Geudens, Celine Aelbrecht, David Ruttens and 10 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Transplant international : official journal of the European Society for Organ Transplantation, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 50% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 citations in OpenAlex.

  1. Review
  2. IsERJ open research · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 3 institutions in 1 country.

Tinne GoosBREATHE, Department of Chronic Diseases and Metabolism, KU Leuven, Leuven, Belgium.
Stijn E VerledenBREATHE, Department of Chronic Diseases and Metabolism, KU Leuven, Leuven, Belgium.
Laurens J De SadeleerBREATHE, Department of Chronic Diseases and Metabolism, KU Leuven, Leuven, Belgium.
Anke Van HerckBREATHE, Department of Chronic Diseases and Metabolism, KU Leuven, Leuven, Belgium.
Annelore SacreasBREATHE, Department of Chronic Diseases and Metabolism, KU Leuven, Leuven, Belgium.
Arno VanstapelBREATHE, Department of Chronic Diseases and Metabolism, KU Leuven, Leuven, Belgium.
Janne KaesBREATHE, Department of Chronic Diseases and Metabolism, KU Leuven, Leuven, Belgium.
Vincent GeudensBREATHE, Department of Chronic Diseases and Metabolism, KU Leuven, Leuven, Belgium.
Celine AelbrechtBREATHE, Department of Chronic Diseases and Metabolism, KU Leuven, Leuven, Belgium.
David RuttensDepartment of Pulmonary Medicine, Ziekenhuis Oost Limburg, Genk, Belgium.
Diether LambrechtsCenter for Cancer Biology, VIB, Leuven, Belgium.
Sascha VermeerCenter for Human Genetics, University Hospitals Leuven, Leuven, Belgium.
Laurens J CeulemansBREATHE, Department of Chronic Diseases and Metabolism, KU Leuven, Leuven, Belgium.
Dirk E Van RaemdonckBREATHE, Department of Chronic Diseases and Metabolism, KU Leuven, Leuven, Belgium.
Laurent GodinasBREATHE, Department of Chronic Diseases and Metabolism, KU Leuven, Leuven, Belgium.
Jonas YserbytBREATHE, Department of Chronic Diseases and Metabolism, KU Leuven, Leuven, Belgium.
Bart M VanaudenaerdeBREATHE, Department of Chronic Diseases and Metabolism, KU Leuven, Leuven, Belgium.
Geert M VerledenBREATHE, Department of Chronic Diseases and Metabolism, KU Leuven, Leuven, Belgium.
Robin VosBREATHE, Department of Chronic Diseases and Metabolism, KU Leuven, Leuven, Belgium.
Wim A WuytsBREATHE, Department of Chronic Diseases and Metabolism, KU Leuven, Leuven, Belgium.
KU Leuven · BEAntwerp University Hospital · BEZiekenhuis Oost-Limburg · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The MUC5B promoter polymorphism (rs35705950) has been associated with interstitial lung disease (ILD) and with prolonged pre-transplant survival in idiopathic pulmonary fibrosis (IPF), but no information is available regarding its prevalence in other respiratory diseases and its influence on post-transplant outcome. We included the Leuven lung transplantation cohort between 1991 and 2015 (

Indexed as

Idiopathic Pulmonary FibrosisLung Diseases, InterstitialGenetic Predisposition to DiseaseHumansMucin-5BPolymorphism, GeneticPromoter Regions, GeneticMUC5B protein, humanMucin-5Bgeneticsinterstitial lung diseaseslung transplantationMUC5Brespiratory diseases

Identifiers

PMID35651878
PMCPMC9149783
OpenAlexW4285741943

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.