Evidence map›Paper›PMID 35651866›Full record

ArticleFrontiers in public health2022

Side Effects of COVID-19 Inactivated Virus vs. Adenoviral Vector Vaccines: Experience of Algerian Healthcare Workers.

Mohamed Lounis, Mohammed Amir Rais, Djihad Bencherit, Hani Amir Aouissi, Adda Oudjedi, Jitka Klugarová, Andrea Pokorná, Miloslav Klugar, Abanoub Riad

Abstract read
In one paragraph

Article in Frontiers in public health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Safety and efficiency of COVID-19 vaccine in North Africa.Human vaccines & immunotherapeutics · 2024
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  11. Screening and confirmation tests for SARS-CoV-2: benefits and drawbacks.Beni-Suef University journal of basic and applied sciences · 2023
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Mohamed LounisDepartment of Agro-Veterinary Science, Faculty of Natural and Life Sciences, University of Ziane Achour, Djelfa, Algeria.
Mohammed Amir RaisDepartment of Dentistry, Faculty of Medicine, University of Algiers Benyoucef Benkhedda, Algiers, Algeria.
Djihad BencheritDepartment of Biology, Faculty of Natural and Life Sciences, University of Ziane Achour, Djelfa, Algeria.
Hani Amir AouissiScientific and Technical Research Center on Arid Regions (CRSTRA), Biskra, Algeria.
Adda OudjediInstitute of Science and Techniques of Physical and Sport Activities, Larbi Ben M'hidi University, Oum El Bouaghi, Algeria.
Jitka KlugarováCzech National Center for Evidence-Based Healthcare and Knowledge Translation (Cochrane Czech Republic, Czech EBHC: JBI Center of Excellence, Masaryk University GRADE Center), Faculty of Medicine, Institute of Biostatistics and Analyses, Masaryk University, Brno, Czechia.
Andrea PokornáCzech National Center for Evidence-Based Healthcare and Knowledge Translation (Cochrane Czech Republic, Czech EBHC: JBI Center of Excellence, Masaryk University GRADE Center), Faculty of Medicine, Institute of Biostatistics and Analyses, Masaryk University, Brno, Czechia.
Miloslav KlugarCzech National Center for Evidence-Based Healthcare and Knowledge Translation (Cochrane Czech Republic, Czech EBHC: JBI Center of Excellence, Masaryk University GRADE Center), Faculty of Medicine, Institute of Biostatistics and Analyses, Masaryk University, Brno, Czechia.
Abanoub RiadCzech National Center for Evidence-Based Healthcare and Knowledge Translation (Cochrane Czech Republic, Czech EBHC: JBI Center of Excellence, Masaryk University GRADE Center), Faculty of Medicine, Institute of Biostatistics and Analyses, Masaryk University, Brno, Czechia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Healthcare workers were prioritized in vaccination campaigns globally because they are exposed to the highest risk of contamination by SARS-CoV-2. This study evaluated the self-reported post-vaccination side effects of inactivated (BBIBP-CorV and CoronaVac) and adenoviral vector-based (AZD1222, Gam-COVID-Vac and Ad26.COV2.S) vaccines among Algerian healthcare workers using a validated questionnaire. The final analysis included 721 healthcare workers, with a predominance of females (59.1%) and younger individuals 20-30 years old (39.4%). Less than half (49.1%) of the respondents reported at least one local side effect, while 53.8% reported at least one systemic side effect. These side effects were more prevalent among viral vector vaccinees than inactivated virus vaccinees. The most common local side effects were injection site pain (39%) and arm pain (25.4%), while fatigue (34.4%), fever (28.4%), headache (24.8%) and myalgia (22.7%) were the most prevalent systemic side effects. The side effects appeared earlier among inactivated virus vaccines recipients and generally lasted for 2 to 3 days for the two vaccinated groups. The risk factors associated with a higher prevalence of side effects included female gender, allergic individuals, individuals with regular medication, those who contracted the COVID-19 disease and those who received two doses for both inactivated and viral-based vaccines groups. Despite the higher prevalence of post-vaccination side effects among adenoviral vector vaccines recipients, both vaccines groups were equally effective in preventing symptomatic infections, and no life-threatening side effects were reported in either vaccine group.

Indexed as

COVID-19Influenza VaccinesAd26COVS1AdultAlgeriaChAdOx1 nCoV-19FemaleHealth PersonnelHumansMalePainSARS-CoV-2Young AdultAd26COVS1ChAdOx1 nCoV-19Influenza Vaccinesadenoviral-based vaccineCOVID-19health workersinactivated virus vaccineside effects

Identifiers

PMID35651866
PMCPMC9149155

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.