Evidence map›Paper›PMID 35651809›Full record

ReviewFrontiers in oncology2022

Non-Coding RNA in Penile Cancer.

Jaqueline Diniz Pinho, Gyl Eanes Barros Silva, Antonio Augusto Lima Teixeira-Júnior, Thalita Moura Silva Rocha, Lecildo Lira Batista, Amanda Marques de Sousa, José de Ribamar Rodrigues Calixto, Rommel Rodrigues Burbano, Carolina Rosal Teixeira de Souza, André Salim Khayat

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Frontiers in oncology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Jaqueline Diniz PinhoZé Doca Center for Higher Studies, State University of Maranhão, Zé Doca, Brazil.
Gyl Eanes Barros SilvaLaboratory of Immunofluorescence and Electron Microscopy, University Hospital of the Federal University of Maranhão, São Luís, Brazil.
Antonio Augusto Lima Teixeira-JúniorLaboratory of Immunofluorescence and Electron Microscopy, University Hospital of the Federal University of Maranhão, São Luís, Brazil.
Thalita Moura Silva RochaLaboratory of Immunofluorescence and Electron Microscopy, University Hospital of the Federal University of Maranhão, São Luís, Brazil.
Lecildo Lira BatistaOncology Research Center, João de Barros Barreto University Hospital, Federal University of Pará, Belém, Brazil.
Amanda Marques de SousaOncology Research Center, João de Barros Barreto University Hospital, Federal University of Pará, Belém, Brazil.
José de Ribamar Rodrigues CalixtoDepartment of Medicine, University Hospital of the Federal University of Maranhão, São Luís, Brazil.
Rommel Rodrigues BurbanoLaboratory Biology Molecular, Ophir Loyola Hospital Ophir, Belém, Brazil.
Carolina Rosal Teixeira de SouzaInstitute of Biological Sciences, Federal University of Pará, Belém, Brazil.
André Salim KhayatOncology Research Center, João de Barros Barreto University Hospital, Federal University of Pará, Belém, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Penile cancer (PC) still presents a health threat for developing countries, in particular Brazil. Despite this, little progress has been made on the study of markers, including molecular ones, that can aid in the correct management of the patient, especially concerning lymphadenectomy. As in other neoplasms, non-coding RNAs (ncRNAs) have been investigated for penile cancer, with emphasis on microRNAs, piRNAs (PIWI-interacting small RNAs), and long non-coding RNAs (LncRNAs). In this context, this review aims to assemble the available knowledge on non-coding RNA linked in PC, contributing to our understanding of the penile carcinogenesis process and addressing their clinical relevance. ncRNAs are part of the novel generation of biomarkers, with high potential for diagnosis and prognosis, orientating the type of treatment. Furthermore, its versatility regarding the use of paraffin samples makes it possible to carry out retrospective studies.

Indexed as

biomarkersmiRNAnon coding RNAs (ncRNAs)penile cancerpiRNAs

Identifiers

PMID35651809
PMCPMC9150447

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.