Evidence map›Paper›PMID 35651725›Full record

ReviewOxidative medicine and cellular longevity2022

Inhibition of Oxidative Stress: An Important Molecular Mechanism of Chinese Herbal Medicine (Astragalus membranaceus, Carthamus tinctorius L., Radix Salvia Miltiorrhizae, etc.) in the Treatment of Ischemic Stroke by Regulating the Antioxidant System.

Xixi Zhao, Yu He, Yangyang Zhang, Haofang Wan, Haitong Wan, Jiehong Yang

RetractedOpen access · hybridAbstract readReviewRetracted Publication
In one paragraph

Review in Oxidative medicine and cellular longevity, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
8.9field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 29 citations in OpenAlex.

  1. Article
  2. The Multitarget Action of Vitamins in the Ischemic Stroke.Current topics in medicinal chemistry · 2024
    Review
  3. Article
  4. Review
  5. Article
  6. Review
  7. TiOAdvances in neurobiology · 2023
    Review
  8. Review
  9. Review
  10. Article
  11. Article
  12. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Xixi ZhaoSchool of Basic Medical Sciences, Zhejiang Chinese Medical University, Hangzhou 310053, China.ORCID https://orcid.org/0000-0003-3178-9561
Yu HeSchool of Pharmaceutical Sciences, Zhejiang Chinese Medical University, Hangzhou 310053, China.ORCID https://orcid.org/0000-0002-5802-051X
Yangyang ZhangSchool of Basic Medical Sciences, Zhejiang Chinese Medical University, Hangzhou 310053, China.ORCID https://orcid.org/0000-0003-0989-0890
Haofang WanAcademy of Chinese Medical Sciences, Zhejiang Chinese Medical University, Hangzhou 310053, China.ORCID https://orcid.org/0000-0001-5055-312X
Haitong WanSchool of Life Sciences, Zhejiang Chinese Medical University, Hangzhou 310053, China.ORCID https://orcid.org/0000-0001-5726-7214
Jiehong YangSchool of Basic Medical Sciences, Zhejiang Chinese Medical University, Hangzhou 310053, China.ORCID https://orcid.org/0000-0002-2758-0485
Zhejiang Chinese Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ischemic stroke is a severe cerebrovascular disease with high mortality and morbidity. Traditional Chinese medicine (TCM) has been utilized for thousands of years in China and is becoming increasingly popular all over the world, especially for the treatments of ischemic stroke. More and more evidences have implicated that oxidative stress has been closely related with ischemic stroke. This review will concentrate on the evidence of the action mechanism of Chinese herbal medicine and its active ingredient in preventing ischemic stroke by modulating redox signaling and oxidative stress pathways and providing references for clinical treatment and scientific research applications.

Indexed as

Carthamus tinctoriusDrugs, Chinese HerbalIschemic StrokeSalvia miltiorrhizaAntioxidantsAstragalus propinquusOxidative StressAntioxidantsDrugs, Chinese Herbal

Identifiers

PMID35651725
PMCPMC9151006
OpenAlexW4281400603

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.