ArticleFrontiers in bioengineering and biotechnology2022
Parametric Design of Hip Implant With Gradient Porous Structure.
Article in Frontiers in bioengineering and biotechnology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
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Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it, 29 citations in OpenAlex.
- Additively manufactured controlled porous orthopedic joint replacement designs to reduce bone stress shielding: a systematic review.Journal of orthopaedic surgery and research · 2023Pooled it
- Research Progress on the Structure and Properties of Medical Bone Implants Based on Additive Manufacturing.Micromachines · 2026Review
- Multiscale Interface Engineering for Orthopedic and Dental Implants: A Review.Journal of functional biomaterials · 2026Review
- 3D-Printed Titanium Trabecular Scaffolds with Sustained Release of Hypoxia-Induced Exosomes for Dual-Mimetic Bone Regeneration.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Layered Gradient Rhombic Dodecahedron Composite Structures for Biomimetic Bone Fabricated via Selective Laser Melting.Micromachines · 2025Article
- Advanced porous hip implants: A comprehensive review.Heliyon · 2024Review
- Debulking of the Femoral Stem in a Primary Total Hip Joint Replacement: A Novel Method to Reduce Stress Shielding.Bioengineering (Basel, Switzerland) · 2024Article
- Tribocorrosion and Surface Protection Technology of Titanium Alloys: A Review.Materials (Basel, Switzerland) · 2023Review
- Study on Surface Roughness, Morphology, and Wettability of Laser-Modified Powder Metallurgy-Processed Ti-Graphite Composite Intended for Dental Application.Bioengineering (Basel, Switzerland) · 2023Article
- Microstructure Optimization for Design of Porous Tantalum Scaffolds Based on Mechanical Properties and Permeability.Materials (Basel, Switzerland) · 2023Article
- Multi-Scale Topology Optimization of Femoral Stem Structure Subject to Stress Shielding Reduce.Materials (Basel, Switzerland) · 2023Article
- A novel hybrid design and modelling of a customised graded Ti-6Al-4V porous hip implant to reduce stress-shielding: An experimental and numerical analysis.Frontiers in bioengineering and biotechnology · 2023Article
- Stress Shielding and Bone Resorption of Press-Fit Polyether-Ether-Ketone (PEEK) Hip Prosthesis: A Sawbone Model Study.Polymers · 2022Article
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Patients who has been implanted with hip implant usually undergo revision surgery. The reason is that high stiff implants would cause non-physiological distribution loadings, which is also known as stress shielding, and finally lead to bone loss and aseptic loosening. Titanium implants are widely used in human bone tissues; however, the subsequent elastic modulus mismatch problem has become increasingly serious, and can lead to stress-shielding effects. This study aimed to develop a parametric design methodology of porous titanium alloy hip implant with gradient elastic modulus, and mitigate the stress-shielding effect. Four independent adjustable dimensions of the porous structure were parametrically designed, and the Kriging algorithm was used to establish the mapping relationship between the four adjustable dimensions and the porosity, surface-to-volume ratio, and elastic modulus. Moreover, the equivalent stress on the surface of the femur was optimized by response surface methodology, and the optimal gradient elastic modulus of the implant was obtained. Finally, through the Kriging approximation model and optimization results of the finite element method, the dimensions of each segment of the porous structure that could effectively mitigate the stress-shielding effect were determined. Experimental results demonstrated that the parameterized design method of the porous implant with gradient elastic modulus proposed in this study increased the strain value on the femoral surface by 17.1% on average. Consequently, the stress-shielding effect of the femoral tissue induced by the titanium alloy implant was effectively mitigated.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.