Evidence map›Paper›PMID 35651427›Full record

ArticleCureus2022

Post Kidney Transplant Cyclosporine-Induced Acute Pancreatitis.

Enas Al-Najada, Asem Alobaidat, Mo'ath M Rabab'ah, Moh'd Bani Salameh, Lean Alkhatib

Open access · diamondAbstract readCase Reports
In one paragraph

Article in Cureus, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Enas Al-NajadaNephrology, Royal Medical Services, Amman, JOR.
Asem AlobaidatPharmacology and Therapeutics, Royal Medical Services, Amman, JOR.
Mo'ath M Rabab'ahNephrology, Royal Medical Services, Amman, JOR.
Moh'd Bani SalamehNephrology, Royal Medical Services, Amman, JOR.
Lean AlkhatibInternal Medicine, Royal Medical Services, Amman, JOR.
King Hussein Medical Center · JO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Drug-induced pancreatitis (DIP) is a rare cause of acute pancreatitis. Efforts have been made to assess the relationship between many drugs and acute pancreatitis. Also, studies have been held to investigate the possible mechanisms of DIP. Cyclosporine is one of the immunosuppressive agents that is still under investigation regarding its association with acute pancreatitis. We report a case of a 21-year-old male patient post kidney transplant who presented with a picture of acute pancreatitis; upon further investigation, the diagnosis of cyclosporine-induced pancreatitis was made by ruling out all other possible causes of acute pancreatitis. Furthermore, he showed significant improvement and was discharged home upon stopping cyclosporine and replacing it with sirolimus, and there was no relapse of pancreatitis in three months of follow-up.  Our case provides evidence that cyclosporine can be a possible cause of pancreatitis in post kidney transplant patients receiving cyclosporine, and how early detection of cyclosporine-induced pancreatitis can significantly improve the patient's condition.

Indexed as

acute pancreatitiscyclosporine-amedication induced pancreatitispost transplantationtransplant nephrology

Identifiers

PMID35651427
PMCPMC9138704
OpenAlexW4282915945

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.