Evidence map›Paper›PMID 35651421›Full record

ArticleCureus2022

In Vivo Transfection of Rat Salivary Glands With Fluorescently Tagged Aquaporin-5 Channel DNA.

Sanjib Adhikary, Max Hennessy, David Goldrich, Victor Ruiz-Velasco, Timothy K Cooper, Neerav Goyal

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cureus, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 58% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Decreased Serum and Salivary Levels of Aquaporin 5 in Oral Lichen Planus.Clinical and experimental dental research · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Sanjib AdhikaryAnesthesiology and Perioperative Medicine, Penn State Health Milton S. Hershey Medical Center, Hershey, USA.
Max HennessyOtolaryngology - Head and Neck Surgery, Penn State Health Milton S. Hershey Medical Center, Hershey, USA.
David GoldrichOtolaryngology - Head and Neck Surgery, Penn State Health Milton S. Hershey Medical Center, Hershey, USA.
Victor Ruiz-VelascoAnesthesiology and Perioperative Medicine, Penn State Health Milton S. Hershey Medical Center, Hershey, USA.
Timothy K CooperPathology, Penn State Health Milton S. Hershey Medical Center, Hershey, USA.
Neerav GoyalOtolaryngology - Head and Neck Surgery, Penn State Health Milton S. Hershey Medical Center, Hershey, USA.
Penn State Milton S. Hershey Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background  The acinar cells of salivary glands are responsible for most saliva production and are, unfortunately, h--ighly radiosensitive. As such, dry mouth or xerostomia is an adverse effect experienced by half of head and neck cancer patients treated with radiation. We evaluate a novel method of gene transfection of aquaporin channels to rat salivary glands. Materials and methods A green fluorescent protein (GFP)-tagged human Aquaporin-5

Indexed as

aquaporin channelsgene deliveryin vivo transfectionsalivasalivary glands

Identifiers

PMID35651421
PMCPMC9138633
OpenAlexW4282935112

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.