ArticleBMC psychiatry2022
Association between smoking and postoperative delirium in surgical patients with pulmonary hypertension: a secondary analysis of a cohort study.
Article in BMC psychiatry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 2 of them syntheses that pooled it.
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Who cites it
9 citing papers in PubMed, 2 syntheses or guidelines pooled it, 13 citations in OpenAlex.
- Factors associated with postoperative delirium in patients undergoing oral and maxillofacial surgery: a meta-analysis of observational study.Frontiers in medicine · 2026Pooled it
- Incidence and risk factors for postoperative delirium after head and neck cancer surgery: an updated meta-analysis.BMC neurology · 2023Pooled it
- Article
- Development and validation of a nomogram model for predicting postoperative delirium in elderly patients with oral cancer: a retrospective study.BMC oral health · 2025Article
- Cardiovascular health score and its association with postoperative delirium: evidence from the Kailuan study.Frontiers in medicine · 2025Article
- High level of systemic immune inflammation index elevates delirium risk among patients in intensive care unit.Scientific reports · 2024Article
- Social vulnerability and surgery outcomes: a cross-sectional analysis.BMC public health · 2024Article
- Article
- Social Vulnerability and Surgery Outcomes: A Cross-sectional Analysis.Research square · 2023Article
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Authors and funding
4 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPrevious studies have declared that smoking was a risk factor for postoperative delirium (POD), but others have inconsistent results. Up till now, the association between smoking and POD has not been verified. This study investigates the relationship between smoking and POD in patients with pulmonary hypertension (PHTN) in the United States.
methodsPatients with PHTN who underwent non-cardiac, non-obstetric surgery were enrolled in the original research completed by Aalap C. et al. We further excluded the patients undergoing intracranial surgery and the patients with sepsis and perioperative stroke to avoid interference with POD assessment. The generalized linear model and generalized additive model were used to explore the relationship between smoking and POD. The propensity score adjustment was used for sensitivity analyses.
resultsFive hundred thirty-nine patients were included in this study. The overall incidence of POD was 3.0% (16/539). After adjusting the potential confounders (age, systemic hypertension, coronary artery disease, COPD, length of surgery, intrathoracic surgery, vascular surgery), a positive relationship was found between smoking status and POD (OR = 4.53, 95% CI: 1.22 to 16.86, P = 0.0243). In addition, the curvilinear relationship between smoking burden (pack-years) and POD is close to a linear relationship.
conclusionSmoking probably shows a positive correlation with POD in patients with PHTN.
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