ArticleBMC infectious diseases2022
Impact of vaccine hesitancy on secondary COVID-19 outbreaks in the US: an age-structured SIR model.
Article in BMC infectious diseases, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Pooled it
- Targeted epidemic mitigation through age-specific dose-response recovery modeling.BMC infectious diseases · 2026Article
- Evaluating ChatGPT's responses to vaccine-related questions: the impact of question framing on content and quality.Translational pediatrics · 2025Article
- Resilience, perceived control, and intention to receive additional vaccines for COVID-19 among healthcare university students: Mediating role of knowledge of vaccine and infection-preventive behaviors.Japan journal of nursing science : JJNS · 2025Article
- Mathematical models to characterize the early phase of the COVID-19 pandemic in New Mexico, USA.Mathematical biosciences and engineering : MBE · 2025Article
- Considerations for mRNA Product Development, Regulation and Deployment Across the Lifecycle.Vaccines · 2025Review
- Vaccine hesitancy in healthcare workers during COVID-19 pandemic: Draw on experience.Journal of preventive medicine and hygiene · 2025Article
- Novel multi-cluster workflow system to support real-time HPC-enabled epidemic science: Investigating the impact of vaccine acceptance on COVID-19 spread.Journal of parallel and distributed computing · 2024Article
- Understanding the determinants of vaccine hesitancy in the United States: A comparison of social surveys and social media.PloS one · 2024Article
- COVID-19 vaccine hesitancy among pregnant women attending public antenatal clinics in Dar es Salaam, Tanzania.Human vaccines & immunotherapeutics · 2023Article
- Institutional trust is a distinct construct related to vaccine hesitancy and refusal.BMC public health · 2023Article
- Societal influence and psychological distress among Indonesian adults in Java on the early Omicron wave of COVID-19.Future science OA · 2023Article
- Framing Effects on Willingness and Perceptions towards COVID-19 Vaccination among University Students in Italy: An Exploratory Study.Vaccines · 2023Article
- Overcoming vaccine hesitancy by multiplex social network targeting: an analysis of targeting algorithms and implications.Applied network science · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
backgroundThe COVID-19 outbreak has become the worst pandemic in at least a century. To fight this disease, a global effort led to the development of several vaccines at an unprecedented rate. There have been, however, several logistic issues with its deployment, from their production and transport, to the hesitancy of the population to be vaccinated. For different reasons, an important amount of individuals is reluctant to get the vaccine, something that hinders our ability to control and-eventually-eradicate the disease. MATERIALS AND
methodsOur aim is to explore the impact of vaccine hesitancy when highly transmissible SARS-CoV-2 variants of concern spread through a partially vaccinated population. To do so, we use age-stratified data from surveys on vaccination acceptance, together with age-contact matrices to inform an age-structured SIR model set in the US.
resultsOur results show that per every one percent decrease in vaccine hesitancy up to 45 deaths per million inhabitants could be averted. A closer inspection of the stratified infection rates also reveals the important role played by the youngest groups. The model captures the general trends of the Delta wave spreading in the US (July-October 2021) with a correlation coefficient of [Formula: see text].
conclusionsOur results shed light on the role that hesitancy plays on COVID-19 mortality and highlight the importance of increasing vaccine uptake in the population, specially among the eldest age groups.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.