ArticleNature2022
Discovery of non-squalene triterpenes.
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Article in Nature, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 58 papers.
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58citing papers in PubMed
12.3field-weighted citation impact, top 1% of its field
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Who cites it
58 citing papers in PubMed, 149 citations in OpenAlex.
- Diverse oxidosqualene cyclases for triterpenoid biosynthesis.Synthetic and systems biotechnology · 2027Review
- Evolutionary, Functional and Mechanistic Characterisation of Microbial Terpene Synthase-Like Genes From Springtails.Angewandte Chemie (International ed. in English) · 2026Article
- Multi-omics and functional analyses in Aesculus wilsonii elucidate the biosynthetic pathways of moretane- and oleanane-type triterpenoids.Plant communications · 2026Article
- Differential Analysis of Sesquiterpenoids ofMolecules (Basel, Switzerland) · 2026Article
- Characterization of an (E, E)-farnesyl pyrophosphate synthase in Saxifraga stolonifera involved in triterpenoid biosynthesis.Plant molecular biology · 2026Article
- From CASP13 to the Nobel Prize: DeepMind's AlphaFold Journey in Revolutionizing Protein Structure Prediction and Beyond.Current protein & peptide science · 2026Review
- Article
- Identification and engineering of a UDP-rhamnosyltransferase fromBiodesign research · 2025Article
- Discovery of an SQS-PSY Domain-Containing Protein inInternational journal of molecular sciences · 2025Article
- Evolution of linear triterpenoid biosynthesis within the Euphorbia genus.Nature communications · 2025Article
- Genome Mining of Terpene Synthases from FourteenMicroorganisms · 2025Article
- The Deep Mining Era: Genomic, Metabolomic, and Integrative Approaches to Microbial Natural Products from 2018 to 2024.Marine drugs · 2025Review
- A large-scale curated and filterable dataset for cryo-EM foundation model pre-training.Scientific data · 2025Article
- A new Clonostachys Sp. ZBS49 filamentous fungus with high production of betulinic acid and its inhibitory effect on liver cancer cells.Microbial cell factories · 2025Article
- Structure of bifunctional variediene synthase yields unique insight on biosynthetic diterpene assembly and cyclization.Nature communications · 2025Article
- Gromomycins: An Unprecedented Class of Triterpene Antibiotics Produced by a Novel Biosynthetic Pathway.Angewandte Chemie (International ed. in English) · 2025Article
- Identification of a key peptide cyclase for novel cyclic peptide discovery in Pseudostellaria heterophylla.Plant communications · 2025Article
- Advances in macromolecular crystallography at the Photon Factory: automation from crystallization to structural determination.Journal of synchrotron radiation · 2025Article
- Synthetic Biology in Natural Product Biosynthesis.Chemical reviews · 2025Review
- A comprehensive review on microbial hyaluronan-degrading enzymes: from virulence factors to biotechnological tools.Bioresources and bioprocessing · 2024Review
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Authors and funding
20 authors at 5 institutions in 3 countries.
Hui Tao *Graduate School of Pharmaceutical Sciences, The University of Tokyo, Tokyo, Japan.ORCID http://orcid.org/0000-0001-7978-5063
Lukas Lauterbach *Kekulé-Institut für Organische Chemie und Biochemie, Rheinische Friedrich-Wilhelms-Universität Bonn, Bonn, Germany.ORCID http://orcid.org/0000-0002-6924-2337
Guangkai Bian *Department of Urology, Zhongnan Hospital of Wuhan University, School of Pharmaceutical Sciences, Wuhan University, Wuhan, China.ORCID http://orcid.org/0000-0002-5804-0262
Rong Chen *Department of Urology, Zhongnan Hospital of Wuhan University, Wuhan, China.
Anwei Hou *Kekulé-Institut für Organische Chemie und Biochemie, Rheinische Friedrich-Wilhelms-Universität Bonn, Bonn, Germany.
Takahiro Mori *Graduate School of Pharmaceutical Sciences, The University of Tokyo, Tokyo, Japan.
Shu ChengKey Laboratory of Combinatorial Biosynthesis and Drug Discovery, Ministry of Education and School of Pharmaceutical Sciences, Wuhan University, Wuhan, China.
Ben HuKey Laboratory of Combinatorial Biosynthesis and Drug Discovery, Ministry of Education and School of Pharmaceutical Sciences, Wuhan University, Wuhan, China.
Li LuKey Laboratory of Combinatorial Biosynthesis and Drug Discovery, Ministry of Education and School of Pharmaceutical Sciences, Wuhan University, Wuhan, China.
Xin MuKey Laboratory of Combinatorial Biosynthesis and Drug Discovery, Ministry of Education and School of Pharmaceutical Sciences, Wuhan University, Wuhan, China.
Min LiKey Laboratory of Combinatorial Biosynthesis and Drug Discovery, Ministry of Education and School of Pharmaceutical Sciences, Wuhan University, Wuhan, China.
Naruhiko AdachiStructural Biology Research Center, Institute of Materials Structure Science, High Energy Accelerator Research Organization (KEK), Tsukuba, Japan.ORCID http://orcid.org/0000-0003-1539-6696
Masato KawasakiStructural Biology Research Center, Institute of Materials Structure Science, High Energy Accelerator Research Organization (KEK), Tsukuba, Japan.
Toshio MoriyaStructural Biology Research Center, Institute of Materials Structure Science, High Energy Accelerator Research Organization (KEK), Tsukuba, Japan.ORCID http://orcid.org/0000-0001-7226-5487
Toshiya SendaStructural Biology Research Center, Institute of Materials Structure Science, High Energy Accelerator Research Organization (KEK), Tsukuba, Japan.ORCID http://orcid.org/0000-0002-5153-928X
Xinghuan WangDepartment of Urology, Zhongnan Hospital of Wuhan University, Wuhan, China.ORCID http://orcid.org/0000-0003-3497-0024
Zixin DengKey Laboratory of Combinatorial Biosynthesis and Drug Discovery, Ministry of Education and School of Pharmaceutical Sciences, Wuhan University, Wuhan, China.
Ikuro AbeGraduate School of Pharmaceutical Sciences, The University of Tokyo, Tokyo, Japan. abei@mol.f.u-tokyo.ac.jp.ORCID http://orcid.org/0000-0002-3640-888X
Jeroen S DickschatKekulé-Institut für Organische Chemie und Biochemie, Rheinische Friedrich-Wilhelms-Universität Bonn, Bonn, Germany. dickschat@uni-bonn.de.ORCID http://orcid.org/0000-0002-0102-0631
Tiangang LiuDepartment of Urology, Zhongnan Hospital of Wuhan University, School of Pharmaceutical Sciences, Wuhan University, Wuhan, China. liutg@whu.edu.cn.ORCID http://orcid.org/0000-0001-8087-0345
Wuhan University · CNHigh Energy Accelerator Research Organization · JPUniversity of Bonn · DEThe University of Tokyo · JPJapan Science and Technology Agency · JP
Funding
No grant is acknowledged in the PubMed record.
Abstract
All known triterpenes are generated by triterpene synthases (TrTSs) from squalene or oxidosqualene
Indexed as
AscomycotaTalaromycesTriterpenesColletotrichumCyclizationDiphosphatesSqualeneSubstrate SpecificityDiphosphatesSqualeneTriterpenes
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.