ArticleScientific reports2022
Processing of fMRI-related anxiety and information flow between brain and body revealed a preponderance of oscillations at 0.15/0.16 Hz.
Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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9 citing papers in PubMed, 13 citations in OpenAlex.
- Cardiac-vagal rhythm echoes on the heartbeat's mechanosensory imprint in the brain.Communications biology · 2025Article
- Autonomic regulation during cognitive reappraisal in major depressive disorder: a study of fMRI correlates.BMC psychiatry · 2025Article
- Article
- Intracortical brain-heart interplay: An EEG model source study of sympathovagal changes.Human brain mapping · 2024Article
- Scan-associated anxiety (scanxiety): the enigma of emotional breathing oscillations at 0.32 Hz (19 bpm).Frontiers in neuroscience · 2024Review
- Pathological Heart Rate Regulation in Apparently Healthy Individuals.Entropy (Basel, Switzerland) · 2023Article
- Analysis of Respiratory Sinus Arrhythmia and Directed Information Flow between Brain and Body Indicate Different Management Strategies of fMRI-Related Anxiety.Biomedicines · 2023Article
- Respiration-entrained brain oscillations in healthy fMRI participants with high anxiety.Scientific reports · 2023Article
- Depression as a cardiovascular disorder: central-autonomic network, brain-heart axis, and vagal perspectives of low mood.Frontiers in network physiology · 2023Article
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Authors and funding
5 authors at 4 institutions in 3 countries.
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No grant is acknowledged in the PubMed record.
Abstract
Slow oscillations of different center frequencies and their coupling play an important role in brain-body interactions. The crucial question analyzed by us is, whether the low frequency (LF) band (0.05-0.15 Hz) or the intermediate frequency (IMF) band (0.1-0.2 Hz) is more eminent in respect of the information flow between body (heart rate and respiration) and BOLD signals in cortex and brainstem. A recently published study with the LF band in fMRI-naïve subjects revealed an intensive information flow from the cortex to the brainstem and a weaker flow from the brainstem to the cortex. The comparison of both bands revealed a significant information flow from the middle frontal gyrus (MFG) to the precentral gyrus (PCG) and from brainstem to PCG only in the IMF band. This pattern of directed coupling between slow oscillations in the cortex and brainstem not only supports the existence of a pacemaker-like structure in brainstem, but provides first evidence that oscillations centered at 0.15/0.16 Hz can also emerge in brain networks. BOLD oscillations in resting states are dominating at ~ 0.08 Hz and respiratory rates at ~ 0.32 Hz. Therefore, the frequency component at ~ 0.16 Hz (doubling-halving 0.08 Hz or 0.32 Hz) is of special interest, because phase coupled oscillations can reduce the energy demand.
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