Evidence map›Paper›PMID 35650263›Full record

ArticleEuropean journal of nuclear medicine and molecular imaging2022

Baseline clinical characteristics predict overall survival in patients undergoing radioligand therapy with [

Philipp E Hartrampf, Anna Katharina Seitz, Franz-Xaver Weinzierl, Sebastian E Serfling, Andreas Schirbel, Steven P Rowe, Hubert Kübler, Andreas K Buck, Rudolf A Werner

Open access · hybridAbstract read
In one paragraph

Article in European journal of nuclear medicine and molecular imaging, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
4.0field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 26 citations in OpenAlex.

  1. Article
  2. Overall Survival with [Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2026
    Article
  3. Radioligand treatment with [European journal of nuclear medicine and molecular imaging · 2026
    Article
  4. Article
  5. First real-world clinical experience with [European journal of nuclear medicine and molecular imaging · 2025
    Article
  6. Review
  7. Pre-treatmentMolecular imaging and biology · 2024
    Article
  8. Early biochemical and radiographic response after one cycle of [European journal of nuclear medicine and molecular imaging · 2023
    Article
  9. SUVEuropean journal of nuclear medicine and molecular imaging · 2023
    Article
  10. Improved quality control of [EJNMMI radiopharmacy and chemistry · 2023
    Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Philipp E Hartrampf *Department of Nuclear Medicine, University Hospital Würzburg, Oberdürrbacherstraße 6, 97080, Würzburg, Germany. Hartrampf_P@ukw.de.
Anna Katharina Seitz *Department of Urology and Paediatric Urology, University Hospital Würzburg, Oberdürrbacherstraße 6, 97080, Würzburg, Germany.
Franz-Xaver WeinzierlDepartment of Nuclear Medicine, University Hospital Würzburg, Oberdürrbacherstraße 6, 97080, Würzburg, Germany.
Sebastian E SerflingDepartment of Nuclear Medicine, University Hospital Würzburg, Oberdürrbacherstraße 6, 97080, Würzburg, Germany.
Andreas SchirbelDepartment of Nuclear Medicine, University Hospital Würzburg, Oberdürrbacherstraße 6, 97080, Würzburg, Germany.
Steven P RoweDepartment of Radiology and Radiological Science, The Russell H Morgan, Johns Hopkins University School of Medicine, 601 N Caroline Str, Baltimore, MD, USA.
Hubert KüblerDepartment of Urology and Paediatric Urology, University Hospital Würzburg, Oberdürrbacherstraße 6, 97080, Würzburg, Germany.
Andreas K Buck *Department of Nuclear Medicine, University Hospital Würzburg, Oberdürrbacherstraße 6, 97080, Würzburg, Germany.
Rudolf A Werner *Department of Nuclear Medicine, University Hospital Würzburg, Oberdürrbacherstraße 6, 97080, Würzburg, Germany.
Universitätsklinikum Würzburg · DEJohns Hopkins University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRadioligand therapy (RLT) with MATERIALS AND

methodsNinety-two mCRPC patients treated with [

resultsBaseline C-reactive protein (CRP; hazard ratio [HR], 1.10, 95% CI 1.02-1.18; P = 0.01), lactate dehydrogenase (LDH; HR, 1.07, 95% CI 1.01-1.11; P = 0.01), aspartate aminotransferase (AST; HR, 1.16, 95% CI 1.06-1.26; P = 0.001), and interval

conclusionIn mCRPC patients treated with [

Indexed as

LutetiumProstatic Neoplasms, Castration-ResistantAspartate AminotransferasesC-Reactive ProteinDipeptidesFollow-Up StudiesHeterocyclic Compounds, 1-RingHumansLactate DehydrogenasesLigandsMaleProstate-Specific AntigenRetrospective StudiesTreatment OutcomeUreaAspartate AminotransferasesC-Reactive ProteinDipeptidesHeterocyclic Compounds, 1-RingLactate DehydrogenasesLigandsLutetiumProstate-Specific AntigenPSMA I&TUrea[177Lu]Lu-PSMA I&TOverall survivalPredictionProstate cancerPSMARadioligand therapy

Identifiers

PMID35650263
PMCPMC9525362
OpenAlexW4281790319

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.