Evidence map›Paper›PMID 35650184›Full record

ArticleNature communications2022

Cell-free prototyping enables implementation of optimized reverse β-oxidation pathways in heterotrophic and autotrophic bacteria.

Bastian Vögeli, Luca Schulz, Shivani Garg, Katia Tarasava, James M Clomburg, Seung Hwan Lee, Aislinn Gonnot, Elamar Hakim Moully, Blaise R Kimmel, Loan Tran and 8 more

Open access · goldAbstract read
In one paragraph

Article in Nature communications, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
6.7field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 76 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Article
  6. Metabolic engineering inaBIOTECH · 2025
    Review
  7. Review
  8. Reconstituting alternative life using the test-bed of cell-free systems.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2025
    Review
  9. Review
  10. Leveraging EngineeredACS synthetic biology · 2025
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Recent progress in engineeringSynthetic and systems biotechnology · 2024
    Review
  18. Review
  19. Article
  20. Synthetic biology (Oxford, England) · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 3 institutions in 1 country.

Bastian VögeliDepartment of Chemical and Biological Engineering and Center for Synthetic Biology, Northwestern University, Evanston, IL, USA.ORCID 0000-0001-7870-7311
Luca SchulzDepartment of Chemical and Biological Engineering and Center for Synthetic Biology, Northwestern University, Evanston, IL, USA.ORCID 0000-0002-4796-2587
Shivani GargLanzaTech Inc., Skokie, IL, USA.
Katia TarasavaDepartment of Chemical, Biological, and Materials Engineering, University of South Florida, Tampa, FL, USA.
James M ClomburgLanzaTech Inc., Skokie, IL, USA.
Seung Hwan LeeDepartment of Chemical, Biological, and Materials Engineering, University of South Florida, Tampa, FL, USA.ORCID 0000-0003-2590-5036
Aislinn GonnotLanzaTech Inc., Skokie, IL, USA.
Elamar Hakim MoullyDepartment of Biomedical Engineering, Northwestern University, Evanston, IL, USA.
Blaise R KimmelDepartment of Chemical and Biological Engineering and Center for Synthetic Biology, Northwestern University, Evanston, IL, USA.ORCID 0000-0002-9582-9887
Loan TranLanzaTech Inc., Skokie, IL, USA.
Hunter ZeleznikLanzaTech Inc., Skokie, IL, USA.
Steven D BrownLanzaTech Inc., Skokie, IL, USA.
Sean D SimpsonLanzaTech Inc., Skokie, IL, USA.
Milan MrksichDepartment of Chemical and Biological Engineering and Center for Synthetic Biology, Northwestern University, Evanston, IL, USA.ORCID 0000-0002-4964-796X
Ashty S KarimDepartment of Chemical and Biological Engineering and Center for Synthetic Biology, Northwestern University, Evanston, IL, USA.ORCID 0000-0002-5789-7715
Ramon GonzalezDepartment of Chemical, Biological, and Materials Engineering, University of South Florida, Tampa, FL, USA. ramongonzale@usf.edu.ORCID 0000-0003-4797-6580
Michael KöpkeLanzaTech Inc., Skokie, IL, USA. michael.koepke@lanzatech.com.ORCID 0000-0003-0642-1415
Michael C JewettDepartment of Chemical and Biological Engineering and Center for Synthetic Biology, Northwestern University, Evanston, IL, USA. m-jewett@northwestern.edu.ORCID 0000-0003-2948-6211
Northwestern University · USUniversity of South Florida · USAZ Technology (United States) · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Carbon-negative synthesis of biochemical products has the potential to mitigate global CO

Indexed as

Carbon CycleEscherichia coliAutotrophic ProcessesFermentationOxidation-Reduction

Identifiers

PMID35650184
PMCPMC9160091
OpenAlexW4281732870

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.