Evidence map›Paper›PMID 35650138›Full record

ArticleInternal medicine (Tokyo, Japan)2022

Fulminant Myocarditis 24 Days after Coronavirus Disease Messenger Ribonucleic Acid Vaccination.

Hiroaki Kawano, Tetsufumi Motokawa, Hirokazu Kurohama, Shinji Okano, Ryohei Akashi, Tsuyoshi Yonekura, Satoshi Ikeda, Koichi Izumikawa, Koji Maemura

Open access · diamondAbstract readCase Reports
In one paragraph

Article in Internal medicine (Tokyo, Japan), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
1.6field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Hiroaki KawanoDepartment of Cardiovascular Medicine, Nagasaki University Graduate School of Biomedical Sciences, Japan.
Tetsufumi MotokawaDepartment of Cardiovascular Medicine, Nagasaki University Graduate School of Biomedical Sciences, Japan.
Hirokazu KurohamaDepartment of Pathology, Nagasaki University Hospital, Japan.
Shinji OkanoDepartment of Pathology, Nagasaki University Hospital, Japan.
Ryohei AkashiDepartment of Cardiovascular Medicine, Nagasaki University Graduate School of Biomedical Sciences, Japan.
Tsuyoshi YonekuraDepartment of Cardiovascular Medicine, Nagasaki University Graduate School of Biomedical Sciences, Japan.
Satoshi IkedaDepartment of Cardiovascular Medicine, Nagasaki University Graduate School of Biomedical Sciences, Japan.
Koichi IzumikawaInfection Control and Education Center, Nagasaki University Hospital, Japan.
Koji MaemuraDepartment of Cardiovascular Medicine, Nagasaki University Graduate School of Biomedical Sciences, Japan.
Nagasaki University · JPNagasaki University Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 60-year-old Japanese woman was hospitalized for cardiogenic shock 24 days after receiving the second dose of the coronavirus disease 2019 BNT162b2 vaccine. Impella CP left ventricular assist device implantation and venoarterial peripheral extracorporeal membranous oxygenation were immediately initiated along with inotropic support and steroid pulse therapy, as an endomyocardial biopsy specimen showed myocarditis. Three weeks later, her cardiac function had recovered, and she was discharged. An immune response associated with the presence of spike protein in cardiac myocytes may be related to myocarditis in the present case because of positive immunostaining for severe acute respiratory syndrome coronavirus 2 spike protein and C4d in the myocardium.

Indexed as

BNT162 VaccineCoronavirusCOVID-19Heart-Assist DevicesMyocarditisFemaleHumansMiddle AgedRNAShock, CardiogenicSpike Glycoprotein, CoronavirusBNT162 VaccineRNASpike Glycoprotein, Coronavirusspike protein, SARS-CoV-2biopsyinflammationpathology

Identifiers

PMID35650138
PMCPMC9424077
OpenAlexW4282931332

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.