Evidence map›Paper›PMID 35649965›Full record

Observational studyTransplantation proceedings

COVID-19 Infection in Kidney Transplant Recipients: A Single Center Experience.

Tulin Akagun, Ozdem Kavraz Tomar, Murat Usta, Suleyman Baylan

Abstract readObservational Study
In one paragraph

Observational study in Transplantation proceedings. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Tulin AkagunDivision of Nephrology, Department of Internal Medicine, Giresun Faculty of Medicine, Giresun University, Giresun, Turkey. Electronic address: tulinozbay@yahoo.com.
Ozdem Kavraz TomarDivision of Nephrology, Department of Internal Medicine, Giresun Faculty of Medicine, Giresun University, Giresun, Turkey.
Murat UstaDepartment of Biochemistry, Department of Internal Medicine, Giresun Faculty of Medicine, Giresun University, Giresun, Turkey.
Suleyman BaylanDepartment of Internal Medicine, Giresun Faculty of Medicine, Giresun University, Giresun, Turkey.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundKidney transplant recipients appear to be particularly high risk for critical COVID-19 illness owing to chronic immunosuppression and coexisting conditions. The aim of this study is to present the clinical characteristics and outcomes of our hospital's kidney transplant recipients who were hospitalized due to COVID-19 infection.

methodsIn our retrospective observational study of COVID-19 PCR-positive patients, 31 of them were hospitalized with COVID-19 pneumonia and they were evaluated using demographics, laboratory data, treatment, and outcome. The prognostic nutritional index (PNI), which is calculated using the serum albumin concentration and total lymphocytic count, was also evaluated. The baseline immunosuppressive therapy of patients at the time of admission and the treatments they received during their hospitalization were recorded. All patients were treated with favipiravir.

resultsOf the 31 renal transplant patients with COVID-19 pneumonia, 20 were male and the mean age was 52.7 ± 13.4. Nine (29%) of the patients died. All patients were treated with favipiravir for 5 days; laboratory tests were recorded before and after treatment. The mean PNI of the patients who survived was higher than the patients who died.

conclusionsThe 9 patients who died had lower PNI and higher neutrophil-to-lymphocyte ratio (NLR), creatinine, l-lactate dehydrogenase (LDH), ferritin, and C-reactive protein (CRP) levels. Hospitalized kidney transplant recipients with COVID-19 have higher rates of mortality. The PNI exhibited good predictive performance and may be a useful clinical marker that can be used for estimating survival in COVID-19 patients.

Indexed as

COVID-19Kidney TransplantationAdultAgedAmidesBiomarkersC-Reactive ProteinCreatinineFemaleFerritinsHumansL-Lactate DehydrogenaseMaleMiddle AgedPyrazinesRetrospective StudiesAmidesBiomarkersC-Reactive ProteinCreatininefavipiravirFerritinsL-Lactate DehydrogenasePyrazinesSerum Albumin

Identifiers

PMID35649965
PMCPMC8995207

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.