Evidence map›Paper›PMID 35649961›Full record

ArticleChembiochem : a European journal of chemical biology2022

Luminescent Assay for the Screening of SARS-CoV-2 M

Daan Sondag, Jona Merx, Emiel Rossing, Thomas J Boltje, Dennis W P M Löwik, Frank H T Nelissen, Mark van Geffen, Cornelis van 't Veer, Waander L van Heerde, Floris P J T Rutjes

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Chembiochem : a European journal of chemical biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 10 citations in OpenAlex.

  1. Synthesis of Caged Aminoluciferin Peptides.Methods in molecular biology (Clifton, N.J.) · 2025
    Article
  2. Acta pharmaceutica Sinica. B · 2024
    Review
  3. Article
  4. Luminescent Assay for the Screening of SARS-CoV-2 MChembiochem : a European journal of chemical biology · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Daan SondagInstitute for Molecules and Materials, Radboud University, 6525, AJ Nijmegen, The Netherlands.
Jona MerxInstitute for Molecules and Materials, Radboud University, 6525, AJ Nijmegen, The Netherlands.
Emiel RossingInstitute for Molecules and Materials, Radboud University, 6525, AJ Nijmegen, The Netherlands.
Thomas J BoltjeInstitute for Molecules and Materials, Radboud University, 6525, AJ Nijmegen, The Netherlands.ORCID 0000-0001-9141-8784
Dennis W P M LöwikInstitute for Molecules and Materials, Radboud University, 6525, AJ Nijmegen, The Netherlands.ORCID 0000-0002-9284-837X
Frank H T NelissenInstitute for Molecules and Materials, Radboud University, 6525, AJ Nijmegen, The Netherlands.
Mark van GeffenEnzyre BV, Novio Tech Campus Transistorweg 5-i, 6534, AT Nijmegen, The Netherlands.
Cornelis van 't VeerEnzyre BV, Novio Tech Campus Transistorweg 5-i, 6534, AT Nijmegen, The Netherlands.
Waander L van HeerdeEnzyre BV, Novio Tech Campus Transistorweg 5-i, 6534, AT Nijmegen, The Netherlands.
Floris P J T RutjesInstitute for Molecules and Materials, Radboud University, 6525, AJ Nijmegen, The Netherlands.ORCID 0000-0003-1538-3852
Radboud University Nijmegen · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Since the outbreak of SARS-CoV-2 in December 2019 millions of infections have been reported globally. The viral chymotrypsin-like main protease (M

Indexed as

COVID-19 Drug TreatmentSARS-CoV-2Antiviral AgentsCoronavirus 3C ProteasesCysteine EndopeptidasesHumansLuminescent MeasurementsMolecular Docking SimulationProtease InhibitorsViral Nonstructural ProteinsAntiviral AgentsCoronavirus 3C ProteasesCysteine EndopeptidasesProtease InhibitorsViral Nonstructural Proteinsenzymesimaging agentsinhibitorsluminescence

Identifiers

PMID35649961
PMCPMC9401586
OpenAlexW4281689980

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.