Evidence map›Paper›PMID 35649631›Full record

ArticleBMJ global health2022

The case for investing in the prevention and control of non-communicable diseases in the six countries of the Gulf Cooperation Council: an economic evaluation.

Khalifa Elmusharaf, Daniel Grafton, Johanna S Jung, Emily Roberts, Yahya Al-Farsi, Ameera Ali Al Nooh, Buthaina Bin Belaila, Amin ElShamy, Hamoud Al-Zuabi, Kholood Ateeq Al Mutawa and 9 more

Registry-linked trialAbstract read
In one paragraph

Article in BMJ global health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07742917 (Application of a Precision Lifestyle Medicine Clinical Program for a Sample of IFHAS Screening Cohort), which is not on this map. Cited by 32 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07742917 narecruitingnot on this mapstarted 2026, after this paper: background citation

Application of a Precision Lifestyle Medicine Clinical Program for a Sample of IFHAS Screening Cohort

TypeinterventionalSponsorInstitute for Healthier Living Abu DhabiRan2026 to 2027Enrolled150ConditionsObese Adults, BMI/Body Composition, Cardiometabolic Risk, Cardiovascular Disease RiskArmsPrecision Lifestyle Medicine Program, Standard IFHAS Care
3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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  9. Modern Management of CKM Syndrome: Use of GLP-1 Receptor Agonists in a Multidisciplinary Setting-Expert Group Recommendations from Kuwait.Diabetes therapy : research, treatment and education of diabetes and related disorders · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Khalifa ElmusharafPublic Health Programme, School of Medicine, University of Limerick, Limerick, Ireland Khalifa_Elmusharaf@yahoo.com.
Daniel GraftonHealth and Development, United Nations Development Programme, Istanbul, Turkey.
Johanna S JungHealth and Development, United Nations Development Programme, New York, New York, USA.
Emily RobertsHealth and Development, United Nations Development Programme, New York, New York, USA.
Yahya Al-FarsiGulf Health Council for Cooperation Council States, Riyadh, Saudi Arabia.
Ameera Ali Al NoohMinistry of Health Bahrain, Manama, Bahrain.
Buthaina Bin BelailaUnited Arab Emirates Ministry of Health & Prevention, Dubai, UAE.
Amin ElShamyUnited Arab Emirates Ministry of Health & Prevention, Dubai, UAE.
Hamoud Al-ZuabiKuwait Ministry of Health, Kuwait City, Kuwait.
Kholood Ateeq Al MutawaMinistry of Public Health Qatar, Doha, Ad Dawhah, Qatar.
Shadha AlraisiGovernment of Oman Ministry of Health, Muscat, Oman.
Najla Al LawatGovernment of Oman Ministry of Health, Muscat, Oman.
Ali GharbalGovernment of Oman Ministry of Health, Muscat, Oman.
Shaker AlomarySaudi Arabia Ministry of Health, Riyadh, Saudi Arabia.
Alexey KulikovUnited Nations Inter-Agency Task Force on the Prevention and Control of NCDs, WHO, Geneva, Switzerland.
Nasim PourghazianNCDs and Mental Health, WHO Regional Office for the Eastern Mediterranean, Cairo, Egypt.
Slim SlamaNCDs Management, WHO, Geneva, Switzerland.
Dudley TarltonHealth and Development, United Nations Development Programme, Geneva, Switzerland.
Nicholas BanatvalaUnited Nations Inter-Agency Task Force on the Prevention and Control of NCDs, WHO, Geneva, Switzerland.

Funding

World Health Organization 001
6 · The paper itself

Abstract

backgroundWhile the non-communicable disease (NCD) burden in the countries of the Gulf Cooperation Council (GCC) (Bahrain, Kuwait, Oman, Qatar, Saudi Arabia and the United Arab Emirates) has surged over the past decades, the costs and return on investment (ROI) of implementing cost-effective, WHO-recommended NCD interventions have not been established.

methodsWe performed an economic analysis to estimate the ROI from scaling up four sets of NCD interventions over 15 years. We estimated the direct costs of the four main NCDs (cancer, diabetes, cardiovascular diseases and chronic respiratory diseases) using a prevalence-based, bottom-up cost-of-illness approach. We estimated indirect costs based on productivity loss due to absenteeism, presenteeism and premature deaths. We costed the scaling up of interventions using the WHO Costing Tool and assessed the health impact of interventions using the OneHealth Tool. We calculated ROI by comparing productivity and social benefits with the total costs of implementing the interventions.

resultsThe four main NCDs cost the GCC economy nearly US$50 billion in 2019, equal to 3.3% of its gross domestic product. The indirect costs are estimated at US$20 billion or 40% of the total burden. Implementing the four modelled intervention packages in the six GCC countries over 15 years will cost US$14 billion, with an ROI of US$4.9 for every US$1 invested and significant health and social benefits, including 290 000 averted premature deaths.

conclusionBased on the results of these six investment cases, we recommend actions to scale up current WHO-recommended cost-effective interventions, strengthen whole-of-government action, drive the NCD legislative agenda, build out the evidence base, generate additional advocacy material, and increase regional collaboration and data-sharing to establish best practices and monitor impact.

Indexed as

Noncommunicable DiseasesCost-Benefit AnalysisDelivery of Health CareHumansKuwaitOmanCancerCardiovascular diseaseDiabetesHealth economicsPrevention strategies

Identifiers

PMID35649631
PMCPMC9161070

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.