ArticleGenome research2022
Snake venom gene expression is coordinated by novel regulatory architecture and the integration of multiple co-opted vertebrate pathways.
Article in Genome research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed, 32 citations in OpenAlex.
- Truncated Life History Underlies Rapid Local Adaptation in Island Rattlesnake Venom Expression.Genome biology and evolution · 2026Article
- Remodeling ofScience advances · 2026Article
- Transcriptomic Insights Into the Evolution of Snake Venom: Mechanisms, Diversity, and Adaptation.Scientifica · 2026Review
- Molecular mechanisms underlying early functional divergence in snake venom inferred from the genomes of two pitviper lineages.BMC biology · 2025Article
- Molecular Mechanisms of Venom Diversity.Toxins · 2025Review
- Unveiling the Evolutionary History of European Vipers and Their Venoms From a Multi-Omic Approach.Molecular ecology · 2025Article
- The gene regulatory mechanisms shaping the heterogeneity of venom production in the Cape coral snake.Genome biology · 2025Article
- Redistribution of Ancestral Functions Underlies the Evolution of Venom Production in Marine Predatory Snails.Molecular biology and evolution · 2025Article
- A Segregating Structural Variant Defines Novel Venom Phenotypes in the Eastern Diamondback Rattlesnake.Molecular biology and evolution · 2025Article
- Host habitat shapes the gut microbiomes of insular reptilian hosts in the Philippines.ISME communications · 2025Article
- A Vision for VenomsBase: An Integrated Knowledgebase for the Study of Venoms and Their Applications.Integrative organismal biology (Oxford, England) · 2025Article
- Review
- Diverse Gene Regulatory Mechanisms Alter Rattlesnake Venom Gene Expression at Fine Evolutionary Scales.Genome biology and evolution · 2024Article
- The genetic regulatory architecture and epigenomic basis for age-related changes in rattlesnake venom.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Distinct regulatory networks control toxin gene expression in elapid and viperid snakes.BMC genomics · 2024Article
- ToxCodAn-Genome: an automated pipeline for toxin-gene annotation in genome assembly of venomous lineages.GigaScience · 2024Article
- Article
- Article
- Gene communities in co-expression networks across different tissues.PLoS computational biology · 2023Article
- Comprehensive isoform-level analysis reveals the contribution of alternative isoforms to venom evolution and repertoire diversity.Genome research · 2023Article
Corrections and comments
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Authors and funding
12 authors at 4 institutions in 2 countries.
Funding
Abstract
Understanding how regulatory mechanisms evolve is critical for understanding the processes that give rise to novel phenotypes. Snake venom systems represent a valuable and tractable model for testing hypotheses related to the evolution of novel regulatory networks, yet the regulatory mechanisms underlying venom production remain poorly understood. Here, we use functional genomics approaches to investigate venom regulatory architecture in the prairie rattlesnake and identify
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.