Evidence map›Paper›PMID 35649186›Full record

ArticleMagnetic resonance in medicine2022

Compact MR-compatible ergometer and its application in cardiac MR under exercise stress: A preliminary study.

Bo He, Yushu Chen, Lei Wang, Yang Yang, Chunchao Xia, Jie Zheng, Fabao Gao

Open access · hybridAbstract read
In one paragraph

Article in Magnetic resonance in medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Bo HeDepartment of Radiology, West China Hospital of Sichuan University, Chengdu, Sichuan, China.
Yushu ChenDepartment of Radiology, West China Hospital of Sichuan University, Chengdu, Sichuan, China.
Lei WangDepartment of Radiology, West China Hospital of Sichuan University, Chengdu, Sichuan, China.
Yang YangIcahn School of Medicine at Mount Sinai, New York, New York, USA.ORCID 0000-0002-2841-4243
Chunchao XiaDepartment of Radiology, West China Hospital of Sichuan University, Chengdu, Sichuan, China.
Jie ZhengMallinckrodt Institute of Radiology, Washington University in St Louis, St. Louis, Missouri, USA.
Fabao GaoDepartment of Radiology, West China Hospital of Sichuan University, Chengdu, Sichuan, China.ORCID 0000-0003-2257-3275
Sichuan University · CNIcahn School of Medicine at Mount Sinai · USWashington University in St. Louis · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo develop a compact MR-compatible ergometer for exercise stress and to initially evaluate the reproducibility of myocardial native T1 and myocardial blood flow (MBF) measurements during exercise stress performed on this ergometer.

methodsThe compact ergometer consists of exercise, workload, and data processing components. The exercise stress can be achieved by pedaling on a pair of cylinders at a predefined frequency with adjustable resistances. Ten healthy subjects were recruited to perform cardiac MRI scans twice in a 3.0T MR scanner, at different days to assess reproducibility. Myocardial native T1 and MBF were acquired at rest and during a moderate exercise. The reproducibility of the two tests was determined by the intra-group correlation coefficient (ICC) and coefficient of variation (CoV).

resultsThe mean exercise intensity in this pilot study was 45 Watts (W), with an exercise duration of 5 min. Stress induced a significant increase in systolic blood pressure (from 113 ± 11 mmHg to 141 ± 12, P < 0.05) and maximal increase in heart rate by 74 ± 19%. The rate pressure product increased two-fold (P < 0.001). Excellent reproducibility was demonstrated in native T1 during the exercise (CoV = 3.0%), whereas the reproducibility of MBF and myocardial perfusion reserve during the exercise was also good (CoV = 10.7% and 8.8%, respectively).

conclusionThis pilot study demonstrated that it is possible to acquire reproducible measurements of myocardial native T1 and MBF during the exercise stress in healthy volunteers using our new compact ergometer.

Indexed as

Coronary CirculationExercise TestHumansMagnetic Resonance ImagingPilot ProjectsReproducibility of Resultscardiac MRexercise stressMR-compatible pedal exercisenative T1perfusion

Identifiers

PMID35649186
PMCPMC9545047
OpenAlexW4281717453

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.