ReviewEnvironmental science & technology2022
Reactions and Products of Squalene and Ozone: A Review.
Review in Environmental science & technology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed.
- Radical-induced autoxidation dominates squalene oxidative aging under environmental conditions.Science advances · 2026Article
- Ozone Reactions with Indoor Surfaces Soiled by Human Skin Oil are Impacted by Manner of Soiling, Relative Humidity, and Air Change Rate.Environmental science & technology · 2026Article
- Association between nocturnal ozone enhancement and daily cardiovascular mortality: A multi-city study in China.Eco-Environment & Health · 2026Article
- Differentiating superficial fungal infection from eczema using a heated dynamic-headspace skin VOC sampler: a hypothesis.Frontiers in medicine · 2026Article
- The Impact of UVC Light on Indoor Air Chemistry: A Modeling Study.Environmental science & technology · 2025Article
- Personal care products disrupt the human oxidation field.Science advances · 2025Article
- Article
- Influence of Germicidal UV (222 nm) Lamps on Ozone, Ultrafine Particles, and Volatile Organic Compounds in Indoor Office Spaces.Environmental science & technology · 2024Article
- Factors Affecting Chlorinated Product Formation from Sodium Hypochlorite Bleach and Limonene Reactions in the Gas Phase.ACS ES&T air · 2024Article
- Nanocluster Aerosols from Ozone-Human Chemistry Are Dominated by Squalene-Ozone Reactions.Environmental science & technology letters · 2024Article
- Ozone generation and chemistry from 222 nm germicidal ultraviolet light in a fragrant restroom.Environmental science. Processes & impacts · 2024Article
- How Does Personal Hygiene Influence Indoor Air Quality?Environmental science & technology · 2024Article
- Body odor samples from infants and post-pubertal children differ in their volatile profiles.Communications chemistry · 2024Article
- Influence of Ventilation on Formation and Growth of 1-20 nm Particles via Ozone-Human Chemistry.Environmental science & technology · 2024Article
- Article
- The Biological and Molecular Action of Ozone and Its Derivatives: State-of-the-Art, Enhanced Scenarios, and Quality Insights.International journal of molecular sciences · 2023Review
- Ozone Generation from a Germicidal Ultraviolet Lamp with Peak Emission at 222 nm.Environmental science & technology letters · 2023Article
- Assessment of indoor air quality in health clubs: insights into (ultra)fine and coarse particles and gaseous pollutants.Frontiers in public health · 2023Article
- Characterization and Quantification of Particle-Bound Criegee Intermediates in Secondary Organic Aerosol.Environmental science & technology · 2022Article
- Stability of Terpenoid-Derived Secondary Ozonides in Aqueous Organic Media.The journal of physical chemistry. A · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
This critical review describes the squalene-ozone (SqOz) reaction, or squalene ozonolysis. Ambient ozone penetrates indoors and drives indoor air chemistry. Squalene, a component of human skin oil, contains six carbon-carbon double bonds and is very reactive with ozone. Bioeffluents from people contribute to indoor air chemistry and affect the indoor air quality, resulting in exposures because people spend the majority of their time indoors. The SqOz reaction proceeds through various formation pathways and produces compounds that include aldehydes, ketones, carboxylic acids, and dicarbonyl species, which have a range of volatilities. In this critical review of SqOz chemistry, information on the mechanism of reaction, reaction probability, rate constants, and reaction kinetics are compiled. Characterizations of SqOz reaction products have been done in laboratory experiments and real-world settings. The effect of multiple environmental parameters (ozone concentration, air exchange rate (AER), temperature, and relative humidity (RH)) in indoor settings are summarized. This critical review concludes by identifying the paucity of available exposure, health, and toxicological data for known reaction products. Key knowledge gaps about SqOz reactions leading to indoor exposures and adverse health outcomes are provided as well as an outlook on where the field is headed.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.