Evidence map›Paper›PMID 35648628›Full record

ArticleThe American journal of sports medicine2022

Returning to Activity After Anterior Cruciate Ligament Revision Surgery: An Analysis of the Multicenter Anterior Cruciate Ligament Revision Study (MARS) Cohort at 2 Years Postoperative.

MARS Group, John P Bigouette, Erin C Owen, Brett Brick A Lantz, Rudolf G Hoellrich, Rick W Wright, Laura J Huston, Amanda K Haas, Christina R Allen, Daniel E Cooper and 80 more

Abstract readMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Article in The American journal of sports medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

90 authors.

MARS GroupInvestigation performed at Slocum Research and Education Foundation, Eugene, Oregon, USA.
John P BigouetteInvestigation performed at Slocum Research and Education Foundation, Eugene, Oregon, USA.
Erin C OwenInvestigation performed at Slocum Research and Education Foundation, Eugene, Oregon, USA.
Brett Brick A LantzInvestigation performed at Slocum Research and Education Foundation, Eugene, Oregon, USA.
Rudolf G HoellrichInvestigation performed at Slocum Research and Education Foundation, Eugene, Oregon, USA.
Rick W WrightInvestigation performed at Slocum Research and Education Foundation, Eugene, Oregon, USA.
Laura J HustonInvestigation performed at Slocum Research and Education Foundation, Eugene, Oregon, USA.
Amanda K HaasInvestigation performed at Slocum Research and Education Foundation, Eugene, Oregon, USA.
Christina R AllenInvestigation performed at Slocum Research and Education Foundation, Eugene, Oregon, USA.
Daniel E CooperInvestigation performed at Slocum Research and Education Foundation, Eugene, Oregon, USA.
Thomas M DeBerardinoInvestigation performed at Slocum Research and Education Foundation, Eugene, Oregon, USA.
Warren R DunnInvestigation performed at Slocum Research and Education Foundation, Eugene, Oregon, USA.
Kurt P SpindlerInvestigation performed at Slocum Research and Education Foundation, Eugene, Oregon, USA.
Michael J StuartInvestigation performed at Slocum Research and Education Foundation, Eugene, Oregon, USA.
John P AlbrightInvestigation performed at Slocum Research and Education Foundation, Eugene, Oregon, USA.
Annunziato Ned AmendolaInvestigation performed at Slocum Research and Education Foundation, Eugene, Oregon, USA.
Christopher C AnnunziataInvestigation performed at Slocum Research and Education Foundation, Eugene, Oregon, USA.
Robert A ArcieroInvestigation performed at Slocum Research and Education Foundation, Eugene, Oregon, USA.
Bernard R BachInvestigation performed at Slocum Research and Education Foundation, Eugene, Oregon, USA.
Champ L BakerInvestigation performed at Slocum Research and Education Foundation, Eugene, Oregon, USA.
Arthur R BartolozziInvestigation performed at Slocum Research and Education Foundation, Eugene, Oregon, USA.
Keith M BaumgartenInvestigation performed at Slocum Research and Education Foundation, Eugene, Oregon, USA.
Jeffery R BechlerInvestigation performed at Slocum Research and Education Foundation, Eugene, Oregon, USA.
Jeffrey H BergInvestigation performed at Slocum Research and Education Foundation, Eugene, Oregon, USA.
Geoffrey A BernasInvestigation performed at Slocum Research and Education Foundation, Eugene, Oregon, USA.
Stephen F BrockmeierInvestigation performed at Slocum Research and Education Foundation, Eugene, Oregon, USA.
Robert H BrophyInvestigation performed at Slocum Research and Education Foundation, Eugene, Oregon, USA.
Charles A Bush-JosephInvestigation performed at Slocum Research and Education Foundation, Eugene, Oregon, USA.
J Brad Butler VInvestigation performed at Slocum Research and Education Foundation, Eugene, Oregon, USA.
James L CareyInvestigation performed at Slocum Research and Education Foundation, Eugene, Oregon, USA.
James E CarpenterInvestigation performed at Slocum Research and Education Foundation, Eugene, Oregon, USA.
Brian J ColeInvestigation performed at Slocum Research and Education Foundation, Eugene, Oregon, USA.
Jonathan M CooperInvestigation performed at Slocum Research and Education Foundation, Eugene, Oregon, USA.
Charles L CoxInvestigation performed at Slocum Research and Education Foundation, Eugene, Oregon, USA.
R Alexander CreightonInvestigation performed at Slocum Research and Education Foundation, Eugene, Oregon, USA.
Tal S DavidInvestigation performed at Slocum Research and Education Foundation, Eugene, Oregon, USA.
David C FlaniganInvestigation performed at Slocum Research and Education Foundation, Eugene, Oregon, USA.
Robert W FrederickInvestigation performed at Slocum Research and Education Foundation, Eugene, Oregon, USA.
Theodore J GanleyInvestigation performed at Slocum Research and Education Foundation, Eugene, Oregon, USA.
Elizabeth A GarofoliInvestigation performed at Slocum Research and Education Foundation, Eugene, Oregon, USA.
Charles J GattInvestigation performed at Slocum Research and Education Foundation, Eugene, Oregon, USA.
Steven R GechaInvestigation performed at Slocum Research and Education Foundation, Eugene, Oregon, USA.
James Robert GiffinInvestigation performed at Slocum Research and Education Foundation, Eugene, Oregon, USA.
Sharon L HameInvestigation performed at Slocum Research and Education Foundation, Eugene, Oregon, USA.
Jo A HannafinInvestigation performed at Slocum Research and Education Foundation, Eugene, Oregon, USA.
Christopher D HarnerInvestigation performed at Slocum Research and Education Foundation, Eugene, Oregon, USA.
Norman Lindsay HarrisInvestigation performed at Slocum Research and Education Foundation, Eugene, Oregon, USA.
Keith S HechtmanInvestigation performed at Slocum Research and Education Foundation, Eugene, Oregon, USA.
Elliott B HershmanInvestigation performed at Slocum Research and Education Foundation, Eugene, Oregon, USA.
David C JohnsonInvestigation performed at Slocum Research and Education Foundation, Eugene, Oregon, USA.
Timothy S JohnsonInvestigation performed at Slocum Research and Education Foundation, Eugene, Oregon, USA.
Morgan H JonesInvestigation performed at Slocum Research and Education Foundation, Eugene, Oregon, USA.
Christopher C KaedingInvestigation performed at Slocum Research and Education Foundation, Eugene, Oregon, USA.
Ganesh V KamathInvestigation performed at Slocum Research and Education Foundation, Eugene, Oregon, USA.
Thomas E KlootwykInvestigation performed at Slocum Research and Education Foundation, Eugene, Oregon, USA.
Bruce A LevyInvestigation performed at Slocum Research and Education Foundation, Eugene, Oregon, USA.
C Benjamin MaInvestigation performed at Slocum Research and Education Foundation, Eugene, Oregon, USA.
G Peter MaiersInvestigation performed at Slocum Research and Education Foundation, Eugene, Oregon, USA.
Robert G MarxInvestigation performed at Slocum Research and Education Foundation, Eugene, Oregon, USA.
Matthew J MatavaInvestigation performed at Slocum Research and Education Foundation, Eugene, Oregon, USA.
Gregory M MathienInvestigation performed at Slocum Research and Education Foundation, Eugene, Oregon, USA.
David R McAllisterInvestigation performed at Slocum Research and Education Foundation, Eugene, Oregon, USA.
Eric C McCartyInvestigation performed at Slocum Research and Education Foundation, Eugene, Oregon, USA.
Robert G McCormackInvestigation performed at Slocum Research and Education Foundation, Eugene, Oregon, USA.
Bruce S MillerInvestigation performed at Slocum Research and Education Foundation, Eugene, Oregon, USA.
Carl W NissenInvestigation performed at Slocum Research and Education Foundation, Eugene, Oregon, USA.
Daniel F O'NeillInvestigation performed at Slocum Research and Education Foundation, Eugene, Oregon, USA.
Brett D OwensInvestigation performed at Slocum Research and Education Foundation, Eugene, Oregon, USA.
Richard D ParkerInvestigation performed at Slocum Research and Education Foundation, Eugene, Oregon, USA.
Mark L PurnellInvestigation performed at Slocum Research and Education Foundation, Eugene, Oregon, USA.
Arun J RamappaInvestigation performed at Slocum Research and Education Foundation, Eugene, Oregon, USA.
Michael A RauhInvestigation performed at Slocum Research and Education Foundation, Eugene, Oregon, USA.
Arthur C RettigInvestigation performed at Slocum Research and Education Foundation, Eugene, Oregon, USA.
Jon K SekiyaInvestigation performed at Slocum Research and Education Foundation, Eugene, Oregon, USA.
Kevin G SheaInvestigation performed at Slocum Research and Education Foundation, Eugene, Oregon, USA.
Orrin H ShermanInvestigation performed at Slocum Research and Education Foundation, Eugene, Oregon, USA.
James R SlauterbeckInvestigation performed at Slocum Research and Education Foundation, Eugene, Oregon, USA.
Matthew V SmithInvestigation performed at Slocum Research and Education Foundation, Eugene, Oregon, USA.
Jeffrey T SpangInvestigation performed at Slocum Research and Education Foundation, Eugene, Oregon, USA.
Ltc Steven J SvobodaInvestigation performed at Slocum Research and Education Foundation, Eugene, Oregon, USA.
Timothy N TaftInvestigation performed at Slocum Research and Education Foundation, Eugene, Oregon, USA.
Joachim J TenutaInvestigation performed at Slocum Research and Education Foundation, Eugene, Oregon, USA.
Edwin M TingstadInvestigation performed at Slocum Research and Education Foundation, Eugene, Oregon, USA.
Armando F VidalInvestigation performed at Slocum Research and Education Foundation, Eugene, Oregon, USA.
Darius G ViskontasInvestigation performed at Slocum Research and Education Foundation, Eugene, Oregon, USA.
Richard A WhiteInvestigation performed at Slocum Research and Education Foundation, Eugene, Oregon, USA.
James S WilliamsInvestigation performed at Slocum Research and Education Foundation, Eugene, Oregon, USA.
Michelle L WolcottInvestigation performed at Slocum Research and Education Foundation, Eugene, Oregon, USA.
Brian R WolfInvestigation performed at Slocum Research and Education Foundation, Eugene, Oregon, USA.
James J YorkInvestigation performed at Slocum Research and Education Foundation, Eugene, Oregon, USA.

Funding

Revision ACL Reconstructions: A Comparative Effectiveness Treatment StudyR01AR060846 · NIAMS · WASHINGTON UNIVERSITY · PI WRIGHT, RICK W · 2011 to 2025
$6.7M
NIAMS NIH HHS R01 AR060846
6 · The paper itself

Abstract

backgroundPatients with anterior cruciate ligament (ACL) revision report lower outcome scores on validated knee questionnaires postoperatively compared to cohorts with primary ACL reconstruction. In a previously active population, it is unclear if patient-reported outcomes (PROs) are associated with a return to activity (RTA) or vary by sports participation level (higher level vs. recreational athletes). HYPOTHESES: Individual RTA would be associated with improved outcomes (ie, decreased knee symptoms, pain, function) as measured using validated PROs. Recreational participants would report lower PROs compared with higher level athletes and be less likely to RTA. STUDY

designCohort study; Level of evidence, 2.

methodsThere were 862 patients who underwent a revision ACL reconstruction (rACLR) and self-reported physical activity at any level preoperatively. Those who did not RTA reported no activity 2 years after revision. Baseline data included patient characteristics, surgical history and characteristics, and PROs: International Knee Documentation Committee questionnaire, Marx Activity Rating Scale, Knee injury and Osteoarthritis Outcome Score, and the Western Ontario and McMaster Universities Osteoarthritis Index. A binary indicator was used to identify patients with same/better PROs versus worse outcomes compared with baseline, quantifying the magnitude of change in each direction, respectively. Multivariable regression models were used to evaluate risk factors for not returning to activity, the association of 2-year PROs after rACLR surgery by RTA status, and whether each PRO and RTA status differed by participation level.

resultsAt 2 years postoperatively, approximately 15% did not RTA, with current smokers (adjusted odds ratio [aOR] = 3.3;

conclusionRecreational-level participants were twice as likely to not RTA compared with those participating at higher levels. Within a previously active cohort, no RTA was a significant predictor of lower PROs after rACLR. However, among patients who did RTA after rACLR, approximately 20% reported lower outcome scores. Most patients with rACLR who were active at baseline improved over time; however, patients who reported worse outcomes at 2 years had a clinically meaningful decline across all PROs.

Indexed as

Anterior Cruciate Ligament InjuriesOsteoarthritisAnterior Cruciate LigamentCohort StudiesFemaleHumansReoperationrecreational athletesreturn to activityrevision anterior cruciate ligament

Identifiers

PMID35648628
PMCPMC9756873

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.