Evidence map›Paper›PMID 35648298›Full record

ArticleClinical rheumatology2022

The impact of a structured weight-loss treatment on physical fitness in patients with psoriatic arthritis and obesity compared to matched controls: a prospective interventional study.

Annelie Bilberg, Ingrid Larsson, Sofia Björkman, Björn Eliasson, Eva Klingberg

Registry-linked trialAbstract read
In one paragraph

Article in Clinical rheumatology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02917434 (Effects of Weight-loss Treatment in Obese Patients With Psoriatic Arthritis), which is not on this map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02917434 nacompletednot on this map

Effects of Weight-loss Treatment in Obese Patients With Psoriatic Arthritis

TypeinterventionalSponsorVastra Gotaland RegionRan2016 to 2021Enrolled90ConditionsObesity, Psoriatic Arthritis, Metabolic Syndrome, PsoriasisArmsVery Low Energy Diet (VLED)
3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Trial
  2. Observational
  3. Handgrip strength testing in rheumatic diseases.Rheumatology international · 2026
    Review
  4. Article
  5. Review
  6. Review
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Annelie BilbergInstitute of Neuroscience and Physiology, Section of Health and Rehabilitation, Physiotherapy, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden. annelie.bilberg@rheuma.gu.se.ORCID http://orcid.org/0000-0002-1822-0285
Ingrid LarssonDepartment of Gastroenterology and Hepatology, Sahlgrenska University Hospital, Gothenburg, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Sofia BjörkmanDepartment of Gastroenterology and Hepatology, Sahlgrenska University Hospital, Gothenburg, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Björn EliassonDepartment of Gastroenterology and Hepatology, Sahlgrenska University Hospital, Gothenburg, Sweden.
Eva KlingbergDepartment of Rheumatology and Inflammation Research, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.

Funding

the swedish state under the agreement between the swedish government and the county councils, the alf-agreement ALFGBG-825511
6 · The paper itself

Abstract

objectivesTo evaluate the effects of weight loss treatment on physical fitness in patients with psoriatic arthritis (PsA) and obesity compared to matched controls.

methodsIn total, 46 patients with PsA (CASPAR) and BMI ≥ 33 kg/m

resultsMedian weight reduction at M6 was 18.9 kg in patients and 23.0 kg in controls, (p = 0.546). At M12, patients' median weight loss from baseline was 16.1 kg, corresponding with significant loss of total fat mass (- 30.1%), and lean mass (total - 7.0%, arm - 13.7%, and leg - 6.0%). Leg muscle strength improved in patients and controls at M6 (p < 0.001) and remained improved at M12 (p < 0.01), while hand-grip strength was unchanged in both groups. Cardiorespiratory fitness increased in controls at M6 (p = 0.018) and M12 (p = 0.028) but not in patients. Physical functioning improved in both groups at M6 (p < 0.001) and remained improved at M12 (p = 0.008) and (p < 0.01), respectively.

conclusionThe intervention resulted in positive effects on body weight and total body fat. Despite reduced lean body mass, the muscle strength did not deteriorate in patients with PsA and controls.

trial registrationClinicalTrials.gov identifier: NCT02917434, registered on September 21, 2016-retrospectively registered.

Indexed as

Arthritis, PsoriaticBody CompositionBody Mass IndexHumansMuscle StrengthObesityPhysical FitnessProspective StudiesWeight LossObesityPhysical fitnessPsoriatic arthritisVery low energy diet treatment

Identifiers

PMID35648298
PMCPMC9474576

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.