Evidence map›Paper›PMID 35647987›Full record

ArticleIndian journal of ophthalmology2022

Cluster outbreak of

Sabia Handa, Simar Rajan Singh, Bhawna Sharma, Vipin Rana, Krinjeela Bazgain, Uday Tekchandani, Shashank Narang, Archana Angrup, Manisha Biswal, Pallab Ray and 1 more

Open access · diamondAbstract read
In one paragraph

Article in Indian journal of ophthalmology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Outbreak Investigation ofPathogens (Basel, Switzerland) · 2026
    Article
  2. Triple Gram-negative bacterial endophthalmitis following intravitreal injection.Journal of ophthalmic inflammation and infection · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Sabia HandaDepartment of Ophthalmology, Advanced Eye Centre, Chandigarh, India.
Simar Rajan SinghDepartment of Ophthalmology, Advanced Eye Centre, Chandigarh, India.
Bhawna SharmaDepartment of Medical Microbiology, Post Graduate Institute of Medical Education and Research, Chandigarh, India.
Vipin RanaDepartment of Ophthalmology, Advanced Eye Centre, Chandigarh, India.
Krinjeela BazgainDepartment of Ophthalmology, Advanced Eye Centre, Chandigarh, India.
Uday TekchandaniDepartment of Ophthalmology, Advanced Eye Centre, Chandigarh, India.
Shashank NarangDepartment of Ophthalmology, Advanced Eye Centre, Chandigarh, India.
Archana AngrupDepartment of Medical Microbiology, Post Graduate Institute of Medical Education and Research, Chandigarh, India.
Manisha BiswalDepartment of Medical Microbiology, Post Graduate Institute of Medical Education and Research, Chandigarh, India.
Pallab RayDepartment of Medical Microbiology, Post Graduate Institute of Medical Education and Research, Chandigarh, India.
Vishali GuptaDepartment of Ophthalmology, Advanced Eye Centre, Chandigarh, India.
Post Graduate Institute of Medical Education and Research · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: To report clinical features, antibiotic susceptibility profile, management, and outcomes of a cluster outbreak of post-cataract surgery Pseudomonas stutzeri endophthalmitis. Methods: This was a hospital-based case series in which 14 patients with acute postoperative endophthalmitis who underwent cataract surgery on the same day were included. Based on severity of presentation, they either underwent pars plana vitrectomy (PPV) with intraocular antibiotics (IOAB) or vitreous tap with IOAB. Vitreous aspirates and environmental surveillance samples were inoculated on culture media and further processed by MALDI-TOF MS for identification and Vitek3 for susceptibility profile. Results: There were 8 females and 6 males with a mean age of 62.14 ± 8.08 years. Presenting signs included corneal folds (100%), hypopyon (57.1%) and fibrin (50%). Ten patients with mild presentation underwent vitreous tap with IOAB. Four patients with severe presentation underwent PPV with IOAB. Pseudomonas stutzeri was isolated from the vitreous samples and was pan-sensitive. Six eyes required multiple interventions. Favorable outcome was obtained in 12 eyes, one eye developed phthisis, and one patient was lost to follow-up. Conclusion: We report the first ever cluster outbreak of Pseudomonas stutzeri endophthalmitis following phacoemulsification with IOL implantation in a single surgeon setting. Majority of the patients had a mild presentation and responded well to targeted anti-microbial treatment.

Indexed as

EndophthalmitisEye Infections, BacterialPhacoemulsificationPseudomonas InfectionsPseudomonas stutzeriAcute DiseaseAgedAnti-Bacterial AgentsCataractDisease OutbreaksFemaleHumansMaleMiddle AgedAnti-Bacterial AgentsAcute endophthalmitiscluster endophthalmitis

Identifiers

PMID35647987
PMCPMC9359233
OpenAlexW4282943594

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.