Evidence map›Paper›PMID 35647958›Full record

ReviewIndian journal of ophthalmology2022

Sympathetic ophthalmia: A comprehensive update.

Swapnil Parchand, Deepshikha Agrawal, Nikitha Ayyadurai, Aniruddha Agarwal, Anil Gangwe, Shashwat Behera, Priyavat Bhatia, Samyak Mulkutkar, Gulshan Barwar, Ramandeep Singh and 2 more

Open access · diamondAbstract readReview
In one paragraph

Review in Indian journal of ophthalmology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
7.6field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it, 37 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Ocular Lymphatics in Health and Disease.Diagnostics (Basel, Switzerland) · 2026
    Review
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Review
  17. Article
  18. Sympathetic ophthalmia or Vogt-Koyanagi-Harada disease: Don't judge a book by its cover.Saudi journal of ophthalmology : official journal of the Saudi Ophthalmological Society
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Swapnil ParchandDepartment of Vitreo-retina and Uvea Services, MGM Eye Institute, Raipur, India.
Deepshikha AgrawalDepartment of Cornea and Anterior segment Services, MGM Eye Institute, Raipur, India.
Nikitha AyyaduraiDepartment of Ophthalmology, Advanced Eye Center, PGIMER, Chandigarh, India.
Aniruddha AgarwalThe Eye Institute, Cleveland Clinic, Abu Dhabi (CCAD), Abu Dhabi, United Arab Emirates (UAE).
Anil GangweDepartment of Vitreo-retina and Uvea Services, MGM Eye Institute, Raipur, India.
Shashwat BeheraDepartment of Vitreo-retina and Uvea Services, MGM Eye Institute, Raipur, India.
Priyavat BhatiaDepartment of Retina and Uvea Services, Sadguru Netra Chikitsalaya, Chitrakoot, Madhya Pradesh, India.
Samyak MulkutkarDepartment of Ophthalmology, PD Hinduja Hospital, Mumbai, Maharashtra, India.
Gulshan BarwarDepartment of Vitreo-retina and Uvea Services, MGM Eye Institute, Raipur, India.
Ramandeep SinghDepartment of Ophthalmology, Advanced Eye Center, PGIMER, Chandigarh, India.
Alok SenDepartment of Retina and Uvea Services, Sadguru Netra Chikitsalaya, Chitrakoot, Madhya Pradesh, India.
Manisha AgarwalDepartment of Uvea Services, Dr Shroff's Charity Eye Hospital, New Delhi, India.
Post Graduate Institute of Medical Education and Research · INDr. Shroff’s Charity Eye Hospital · INP. D. Hinduja Hospital and Medical Research Centre · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sympathetic ophthalmia is a rare, bilateral, granulomatous, panuveitis following penetrating trauma or surgery to one eye. Clinical presentation commonly occurs within the first year of trauma occurrence but can be delayed by several years. It manifests as acute/chronic granulomatous uveitis with yellowish-white choroidal lesions or Dalen-Fuchs nodules. Initially, patients respond rapidly to corticosteroid therapy, but a majority require long-term use of corticosteroid-sparing agents to prevent recurrences. The purpose of this review is to elaborate on the current understanding of the pathophysiology, the importance of multimodal imaging in early diagnosis, and the role of newer immunomodulatory and biological agents in recalcitrant cases.

Indexed as

Ophthalmia, SympatheticAdrenal Cortex HormonesChoroidHumansAdrenal Cortex HormonesDalen–Fuchs nodulegranulomatous uveitisimmunosuppressionocular traumapanuveitissympathetic ophthalmia

Identifiers

PMID35647958
PMCPMC9359263
OpenAlexW4282943883

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.