ReviewIndian journal of ophthalmology2022
Neurotization of the human cornea - A comprehensive review and an interim report.
Review in Indian journal of ophthalmology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
11 citing papers in PubMed.
- Noncontact Esthesiometer: Large Cohort Study on Agreement with Contact Method and Correlations with Corneal Nerves and Ocular Surface.Ophthalmology science · 2026Article
- Corneal neurotization for the treatment of neurotrophic keratopathy.Current opinion in ophthalmology · 2025Review
- CORONIS symposium 2023: Scientific and clinical frontiers in ocular surface innervation.Acta ophthalmologica · 2025Article
- Allogeneic anterior lens capsule transplantation (ALCT) for the management of HSV neurotrophic keratitis.American journal of ophthalmology case reports · 2025Article
- Corneal Epithelial Changes in Diabetic Patients: A Review.International journal of molecular sciences · 2024Review
- Corneal Neurotization-Indications, Surgical Techniques and Outcomes.Journal of clinical medicine · 2023Review
- Frequency and visual outcomes of herpes simplex keratitis in a Kuwaiti tertiary referral center.Medical hypothesis, discovery & innovation ophthalmology journal · 2023Article
- Clinical outcomes of corneal neurotization using sural nerve graft in neurotrophic keratopathy.PloS one · 2023Article
- Commentary: Congenital corneal anesthesia: A rare form of type-4 familial dysautonomia.Indian journal of ophthalmology · 2022Article
- Commentary: Corneal neurotization.Indian journal of ophthalmology · 2022Article
- Clinical strategies to prevent recurrence of Herpes simplex and Herpes zoster following ocular surgery: A comprehensive review with practical guidelines.Survey of ophthalmologyReview
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14 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We present a comprehensive review of existing literature on surgical corneal neurotization (SCN) as a treatment modality for neurotrophic keratopathy (NK) with an interim report of seven cases where SCN was performed using the indirect approach and followed up till 18 months postoperatively to look for improvement in ocular surface, corneal sensations, and nerve regeneration by using in vivo confocal microscopy (IVCM). A literature search was performed for publications with keywords "corneal nerves," "neurotization," "esthesiometry," "corneal anesthesia," and "neurotrophic keratopathy." All literature available till December 31, 2020 was reviewed and included to describe NK and its management options, particularly SCN. NK is associated with absent or reduced corneal sensations and is managed using a step-ladder algorithm ranging from medical management for symptomatic relief to surgical corneal neurotization. Both direct and indirect approaches of SCN have a favorable outcome with reduced surgical morbidity in the indirect approach using sural nerve graft. Post neurotization, corneal sensation recovery may take up to 3-6 months, while nerve regeneration on confocal microscopy can take as long as 6 months-1 year.
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