Evidence map›Paper›PMID 35647874›Full record

ArticleMicrobiology spectrum2022

GpsB Coordinates Cell Division and Cell Surface Decoration by Wall Teichoic Acids in Staphylococcus aureus.

Lauren R Hammond, Michael D Sacco, Sebastian J Khan, Catherine Spanoudis, Abigail Hough-Neidig, Yu Chen, Prahathees J Eswara

Open access · goldAbstract read
In one paragraph

Article in Microbiology spectrum, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
5.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 28 citations in OpenAlex.

  1. Article
  2. Article
  3. How do spherical bacteria regulate cell division?Biochemical Society transactions · 2025
    Review
  4. A novel polysaccharide in the envelope ofJournal of bacteriology · 2025
    Article
  5. Article
  6. Article
  7. eLife · 2024
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Identification of FacZ as a division site placement factor inbioRxiv : the preprint server for biology · 2023
    Article
  13. Review
  14. Article
  15. Review
  16. The roles of GpsB and DivIVA inFrontiers in microbiology · 2023
    Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Lauren R Hammond *Department of Cell Biology, Microbiology, and Molecular Biology, University of South Florida, Tampa, Florida, USA.
Michael D Sacco *Department of Molecular Medicine, University of South Florida, Tampa, Florida, USA.
Sebastian J KhanDepartment of Cell Biology, Microbiology, and Molecular Biology, University of South Florida, Tampa, Florida, USA.
Catherine SpanoudisDepartment of Cell Biology, Microbiology, and Molecular Biology, University of South Florida, Tampa, Florida, USA.
Abigail Hough-NeidigDepartment of Cell Biology, Microbiology, and Molecular Biology, University of South Florida, Tampa, Florida, USA.
Yu ChenDepartment of Molecular Medicine, University of South Florida, Tampa, Florida, USA.ORCID 0000-0002-5115-3600
Prahathees J EswaraDepartment of Cell Biology, Microbiology, and Molecular Biology, University of South Florida, Tampa, Florida, USA.ORCID 0000-0003-4430-261X
University of South Florida · US

Funding

Division site determination in Gram-positive bacteriaR35GM133617 · NIGMS · UNIVERSITY OF SOUTH FLORIDA · PI ESWARA, PRAHATHEES JAI · 2019 to 2023
$2.3M
Characterization and Inhibition of protein-protein interactions involving Staphylococcus aureus GpsBR21AI164775 · NIAID · UNIVERSITY OF SOUTH FLORIDA · PI CAI, JIANFENG, CHEN, YU · 2021 to 2022
$411k
NIAID NIH HHS R21 AI164775NIGMS NIH HHS R35 GM133617
6 · The paper itself

Abstract

Bacterial cell division is a complex and highly regulated process requiring the coordination of many different proteins. Despite substantial work in model organisms, our understanding of the systems regulating cell division in noncanonical organisms, including critical human pathogens, is far from complete. One such organism is Staphylococcus aureus, a spherical bacterium that lacks known cell division regulatory proteins. Recent studies on GpsB, a protein conserved within the

Indexed as

Staphylococcal InfectionsTeichoic AcidsBacterial ProteinsCell DivisionCell WallHumansStaphylococcus aureusVirulence FactorsBacterial ProteinsTeichoic AcidsVirulence Factorscell divisioncell wallcytokinesisFtsZGpsBPBPsuppressorsWTA

Identifiers

PMID35647874
PMCPMC9241681
OpenAlexW4281623817

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.