Evidence map›Paper›PMID 35647863›Full record

ArticleJournal of the American Chemical Society2022

Effect of Ligands and Transducers on the Neurotensin Receptor 1 Conformational Ensemble.

Austin D Dixon, Asuka Inoue, Scott A Robson, Kelly J Culhane, Jonathan C Trinidad, Sivaraj Sivaramakrishnan, Fabian Bumbak, Joshua J Ziarek

Abstract read
In one paragraph

Article in Journal of the American Chemical Society, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Neurotensin and Alcohol Use Disorders: Towards a Pharmacological Treatment.International journal of molecular sciences · 2023
    Review
  9. Article
  10. Article
  11. A method for selectiveProtein science : a publication of the Protein Society · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Austin D DixonDepartment of Molecular and Cellular Biochemistry, Indiana University, Bloomington, Indiana 47405, United States.ORCID 0000-0001-8676-915X
Asuka InoueGraduate School of Pharmaceutical Sciences, Tohoku University, Sendai 980-8578, Miyagi, Japan.ORCID 0000-0003-0805-4049
Scott A RobsonDepartment of Molecular and Cellular Biochemistry, Indiana University, Bloomington, Indiana 47405, United States.ORCID 0000-0002-0529-0399
Kelly J CulhaneDepartment of Genetics, Cell Biology, and Development, University of Minnesota, Minneapolis, Minnesota 55455, United States.ORCID 0000-0001-8075-4782
Jonathan C TrinidadLaboratory for Biological Mass Spectrometry, Department of Chemistry, Indiana University, Bloomington, Indiana 47405, United States.ORCID 0000-0002-8279-1509
Sivaraj SivaramakrishnanDepartment of Genetics, Cell Biology, and Development, University of Minnesota, Minneapolis, Minnesota 55455, United States.ORCID 0000-0002-9541-6994
Fabian BumbakDepartment of Molecular and Cellular Biochemistry, Indiana University, Bloomington, Indiana 47405, United States.ORCID 0000-0003-2739-8197
Joshua J ZiarekDepartment of Molecular and Cellular Biochemistry, Indiana University, Bloomington, Indiana 47405, United States.ORCID 0000-0002-3740-9999

Funding

Training Research Educators in Minnesota (TREM) whilst increasing diversityK12GM119955 · NIGMS · UNIVERSITY OF MINNESOTA · PI David Irwin Greenstein, Julia Willett · 2017 to 2026
$6.5M
Emergent cellular functions of GPCRs and myosinsR35GM126940 · NIGMS · UNIVERSITY OF MINNESOTA · PI Sivaraj Sivaramakrishnan · 2018 to 2026
$3.8M
The role of dynamics in GPCR and arrestin allosteryR35GM143054 · NIGMS · TRUSTEES OF INDIANA UNIVERSITY · PI ZIAREK, JOSHUA JAMES · 2021 to 2025
$2.1M
Deciphering GPCR signal transduction through NMR structure and dynamics studiesR00GM115814 · NIGMS · TRUSTEES OF INDIANA UNIVERSITY · PI ZIAREK, JOSHUA JAMES · 2017 to 2019
$747k
NIGMS NIH HHS K12 GM119955NIGMS NIH HHS R00 GM115814NIGMS NIH HHS R35 GM126940NIGMS NIH HHS R35 GM143054
6 · The paper itself

Abstract

Using a discrete, intracellular

Indexed as

Receptors, G-Protein-CoupledReceptors, NeurotensinLigandsMembrane ProteinsProtein ConformationTransducersLigandsMembrane ProteinsReceptors, G-Protein-CoupledReceptors, Neurotensin

Identifiers

PMID35647863
PMCPMC9936889

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.