Evidence map›Paper›PMID 35647696›Full record

ArticleMicrobiology spectrum2022

Evaluation of a Multiplex Bead Assay against Single-Target Assays for Detection of IgG Antibodies to SARS-CoV-2.

Kaitlin F Mitchell, Christina M Carlson, Douglas Nace, Brian S Wakeman, Jan Drobeniuc, Glenn P Niemeyer, Bonnie Werner, Alex R Hoffmaster, Panayampalli S Satheshkumar, Amy J Schuh and 2 more

Open access · goldAbstract read
In one paragraph

Article in Microbiology spectrum, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.8field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 18 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Kaitlin F MitchellLaboratory Leadership Service assigned to Center for Global Health, Centers for Disease Control and Preventiongrid.416738.f, Atlanta, Georgia, USA.
Christina M CarlsonMalaria Branch, Division of Parasitic Diseases and Malaria, Centers for Disease Control and Preventiongrid.416738.f, Atlanta, Georgia, USA.
Douglas NaceMalaria Branch, Division of Parasitic Diseases and Malaria, Centers for Disease Control and Preventiongrid.416738.f, Atlanta, Georgia, USA.
Brian S WakemanMalaria Branch, Division of Parasitic Diseases and Malaria, Centers for Disease Control and Preventiongrid.416738.f, Atlanta, Georgia, USA.
Jan DrobeniucLaboratory Task Force, COVID-19 Response, Centers for Disease Control and Preventiongrid.416738.f, Atlanta, Georgia, USA.
Glenn P NiemeyerLaboratory Task Force, COVID-19 Response, Centers for Disease Control and Preventiongrid.416738.f, Atlanta, Georgia, USA.
Bonnie WernerLaboratory Task Force, COVID-19 Response, Centers for Disease Control and Preventiongrid.416738.f, Atlanta, Georgia, USA.
Alex R HoffmasterLaboratory Task Force, COVID-19 Response, Centers for Disease Control and Preventiongrid.416738.f, Atlanta, Georgia, USA.
Panayampalli S SatheshkumarLaboratory Task Force, COVID-19 Response, Centers for Disease Control and Preventiongrid.416738.f, Atlanta, Georgia, USA.
Amy J SchuhLaboratory Task Force, COVID-19 Response, Centers for Disease Control and Preventiongrid.416738.f, Atlanta, Georgia, USA.ORCID 0000-0001-8069-349X
Venkatachalam UdhayakumarMalaria Branch, Division of Parasitic Diseases and Malaria, Centers for Disease Control and Preventiongrid.416738.f, Atlanta, Georgia, USA.
Eric RogierMalaria Branch, Division of Parasitic Diseases and Malaria, Centers for Disease Control and Preventiongrid.416738.f, Atlanta, Georgia, USA.ORCID 0000-0001-7375-8304
Centers for Disease Control and Prevention · US

Funding

CDC HHS
6 · The paper itself

Abstract

Serological assays for SARS-CoV-2 antibodies must be validated for performance with a large panel of clinical specimens. Most existing assays utilize a single antigen target and may be subject to reduced diagnostic specificity. This study evaluated a multiplex assay that detects antibodies to three SARS-CoV-2 targets. Human serum specimens (

Indexed as

COVID-19SARS-CoV-2Antibodies, ViralHumansImmunoglobulin GSeroepidemiologic StudiesSpike Glycoprotein, CoronavirusAntibodies, ViralImmunoglobulin GSpike Glycoprotein, Coronavirusspike protein, SARS-CoV-2antibodyCOVID-19multiplex bead assaySARS-CoV-2

Identifiers

PMID35647696
PMCPMC9241621
OpenAlexW4281636110

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.