Evidence map›Paper›PMID 35647692›Full record

ArticleMicrobiology spectrum2022

Roles of SmeYZ, SbiAB, and SmeDEF Efflux Systems in Iron Homeostasis of Stenotrophomonas maltophilia.

Chao-Jung Wu, Yu Chen, Li-Hua Li, Cheng-Mu Wu, Yi-Tsung Lin, Cheng-Hua Ma, Tsuey-Ching Yang

Open access · goldAbstract read
In one paragraph

Article in Microbiology spectrum, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
3.7field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 19 citations in OpenAlex.

  1. Molecular Regulation of Biofilm Development inPathogens (Basel, Switzerland) · 2026
    Review
  2. Review
  3. Review
  4. Article
  5. Contribution of fepABMC microbiology · 2025
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  6. Article
  7. Roles of theFrontiers in cellular and infection microbiology · 2025
    Article
  8. Article
  9. Article
  10. Identification of the Major Facilitator Superfamily Efflux Pump KpsrMFS inInternational journal of molecular sciences · 2024
    Article
  11. Frontiers in microbiology · 2024
    Review
  12. Antibiotics (Basel, Switzerland) · 2023
    Article
  13. Versatility ofHeliyon · 2023
    Review
  14. TheMicrobiology spectrum · 2022
    Article
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Chao-Jung WuDepartment of Biotechnology and Laboratory Science in Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan.ORCID 0000-0002-5867-9402
Yu ChenDepartment of Biotechnology and Laboratory Science in Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan.
Li-Hua LiSchool of Medical Laboratory Science and Biotechnology, College of Medical Science and Technology, Taipei Medical University, Taipei, Taiwan.
Cheng-Mu WuDepartment of Biotechnology and Laboratory Science in Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan.
Yi-Tsung LinDivision of Infectious Diseases, Department of Medicine, Taipei Veterans General Hospitalgrid.278247.c, Taipei, Taiwan.
Cheng-Hua MaDepartment of Chemistry, National Taiwan Universitygrid.19188.39, Taipei, Taiwan.
Tsuey-Ching YangDepartment of Biotechnology and Laboratory Science in Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan.ORCID 0000-0003-4111-6870
National Yang Ming Chiao Tung University · TWNational Taiwan University · TWTaipei Veterans General Hospital · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Stenotrophomonas maltophilia, a nonfermenting Gram-negative rod, is frequently isolated from the environment and is emerging as a multidrug-resistant global opportunistic pathogen. S. maltophilia harbors eight RND-type efflux pumps that contribute to multidrug resistance and physiological functions. Among the eight efflux pumps, SmeYZ pump is constitutively highly expressed. In our previous study, we demonstrated that loss-of-function of the SmeYZ pump results in pleiotropic phenotypes, including abolished swimming motility, decreased secreted protease activity, and compromised tolerance to oxidative stress and antibiotics. In this study, we attempted to elucidate the underlying mechanisms responsible for

Indexed as

Stenotrophomonas maltophiliaAnti-Bacterial AgentsBacterial ProteinsHomeostasisIronMembrane Transport ProteinsMicrobial Sensitivity TestsSiderophoresAnti-Bacterial AgentsBacterial ProteinsIronMembrane Transport ProteinsSiderophoresefflux pumpiron homeostasisStenotrophomonas maltophilia

Identifiers

PMID35647692
PMCPMC9241820
OpenAlexW4281989181

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.