Evidence map›Paper›PMID 35647663›Full record

ArticleInfection and immunity2022

RNA-Based Therapy for Cryptosporidium parvum Infection: Proof-of-Concept Studies.

A Castellanos-Gonzalez, A Sadiqova, J Ortega-Mendez, A C White

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Infection and immunity, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.1field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Review
  3. Current tropical medicine reports · 2024
    Review
  4. RNA-Based Vaccines and Therapeutics Against Intracellular Pathogens.Methods in molecular biology (Clifton, N.J.) · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

A Castellanos-GonzalezDepartment of Internal Medicine, Infectious Diseases Division, University of Texas Medical Branch, Galveston, Texas, USA.ORCID 0000-0001-9092-153X
A SadiqovaDepartment of Internal Medicine, Infectious Diseases Division, University of Texas Medical Branch, Galveston, Texas, USA.
J Ortega-MendezDepartment of Internal Medicine, Infectious Diseases Division, University of Texas Medical Branch, Galveston, Texas, USA.
A C WhiteDepartment of Internal Medicine, Infectious Diseases Division, University of Texas Medical Branch, Galveston, Texas, USA.
The University of Texas Medical Branch at Galveston · US

Funding

Development of a novel RNA interference method to reduce Cryptosporidium infectionR21AI151901 · NIAID · UNIVERSITY OF TEXAS MED BR GALVESTON · PI CASTELLANOS-GONZALEZ, ALEJANDRO · 2020 to 2021
$435k
Development of a rapid method to silence genes in CryptosporidiumR21AI126275 · NIAID · UNIVERSITY OF TEXAS MED BR GALVESTON · PI CASTELLANOS-GONZALEZ, ALEJANDRO · 2016 to 2017
$426k
NIAID NIH HHS R21 AI126275NIAID NIH HHS R21 AI151901
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

CryptosporidiosisCryptosporidiumCryptosporidium parvumAnimalsLiposomesMiceMice, SCIDNanoparticlesRNALipid NanoparticlesLiposomesRNAArgonautecryptosporidiosisCryptosporidiumgene silencingNDKsiRNA

Identifiers

PMID35647663
PMCPMC9302151
OpenAlexW4281941439

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.