Evidence map›Paper›PMID 35647451›Full record

ArticleACS omega2022

Systematic Development of Solid Lipid Nanoparticles of Abiraterone Acetate with Improved Oral Bioavailability and Anticancer Activity for Prostate Carcinoma Treatment.

Sarwar Beg, Ankit K Malik, Mohammad Javed Ansari, Asrar A Malik, Ahmed Mahmoud Abdelhaleem Ali, Abdulrahman Theyab, Mohammad Algahtani, Waleed H Almalki, Khalid S Alharbi, Sattam K Alenezi and 3 more

Open access · goldAbstract read
In one paragraph

Article in ACS omega, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
8.3field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 41 citations in OpenAlex.

  1. Review
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  5. Review
  6. Formulation, Optimization, andCurrent pharmaceutical design · 2025
    Article
  7. Nanoparticle tools for maximizing oral drug delivery.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica · 2025
    Review
  8. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 10 institutions in 2 countries.

Sarwar BegDepartment of Pharmaceutics, School of Pharmaceutical Education and Research, Nanomedicine Research Lab, Jamia Hamdard, New Delhi 110062, India.ORCID https://orcid.org/0000-0002-3304-2712
Ankit K MalikDepartment of Pharmaceutics, School of Pharmaceutical Education and Research, Nanomedicine Research Lab, Jamia Hamdard, New Delhi 110062, India.
Mohammad Javed AnsariDepartment of Pharmaceutics, College of Pharmacy, Prince Sattam Bin Abdulaziz University, Al-kharj 16278, Saudi Arabia.
Asrar A MalikSchool of Basic Sciences and Research, Department of Life Sciences, Sharda University, Greater Noida, Uttar Pradesh 201306, India.
Ahmed Mahmoud Abdelhaleem AliDepartment of Pharmaceutics and Industrial Pharmacy, College of Pharmacy, Taif University, P.O. Box 11099, Taif 21944, Saudi Arabia.ORCID https://orcid.org/0000-0002-4370-007X
Abdulrahman TheyabDepartment of Laboratory Medicine, Security Forces Hospital, Mecca 21955, Saudi Arabia.
Mohammad AlgahtaniDepartment of Laboratory Medicine, Security Forces Hospital, Mecca 21955, Saudi Arabia.
Waleed H AlmalkiDepartment of Pharmacology and Toxicology, College of Pharmacy, Umm Al-Qura University, Al-Abidiyah 21955, Saudi Arabia.
Khalid S AlharbiDepartment of Pharmacology, College of Pharmacy, Jouf University, Sakakah 72388, Saudi Arabia.
Sattam K AleneziDepartment of Pharmacology and Toxicology, Unaizah College of Pharmacy, Qassim University, Qassim 52222, Saudi Arabia.
Md Abul BarkatDepartment of Pharmaceutics, College of Pharmacy, University of Hafr, Al Batin 39524, Saudi Arabia.
Mahfoozur RahmanDepartment of Pharmaceutical Sciences, Shalom Institute of Health and Allied Sciences, Sam Higginbottom University of Agriculture, Technology and Sciences, Allahabad 211007, India.
Hani ChoudhryDepartment of Biochemistry, Cancer Metabolism and Epigenetic Unit, Faculty of Science, King Fahd Center for Medical Research, King Abdulaziz University, Jeddah 21589, Saudi Arabia.
Jamia Hamdard · INSecurity Forces Hospital · SAJouf University · SAKing Abdulaziz University · SAPrince Sattam Bin Abdulaziz University · SAQassim University · SASam Higginbottom Institute of Agriculture · INTaif University · SAUmm al-Qura University · SAUniversity of Hafr Al-Batin · SA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In the present work, an attempt was undertaken to improve the oral bioavailability and anticancer activity of abiraterone acetate. Solid lipid nanoparticles (SLNs) were developed using the quality by design (QbD) principles and evaluated through

Identifiers

PMID35647451
PMCPMC9134222
OpenAlexW4281630763

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.