Evidence map›Paper›PMID 35647394›Full record

ArticleAdvances in radiation oncology

Effect of Hyaluronate Acid Injection on Dose-Volume Parameters in Brachytherapy for Cervical Cancer.

Rei Kobayashi, Naoya Murakami, Takahito Chiba, Kae Okuma, Koji Inaba, Kana Takahashi, Tomoya Kaneda, Tairo Kashihara, Ayaka Takahashi, Yuri Shimizu and 4 more

Abstract read
In one paragraph

Article in Advances in radiation oncology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

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  6. Role of rectal spacers in gynecological cancer radiotherapy: reducing rectal dose and treatment-related toxicity.Reports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Rei KobayashiDepartment of Radiation Oncology, National Cancer Center Hospital, Tokyo, Japan.
Naoya MurakamiDepartment of Radiation Oncology, National Cancer Center Hospital, Tokyo, Japan.
Takahito ChibaDepartment of Medical Physics, National Cancer Center Hospital, Tokyo, Japan.
Kae OkumaDepartment of Radiation Oncology, National Cancer Center Hospital, Tokyo, Japan.
Koji InabaDepartment of Radiation Oncology, National Cancer Center Hospital, Tokyo, Japan.
Kana TakahashiDepartment of Radiation Oncology, National Cancer Center Hospital, Tokyo, Japan.
Tomoya KanedaDepartment of Radiation Oncology, National Cancer Center Hospital, Tokyo, Japan.
Tairo KashiharaDepartment of Radiation Oncology, National Cancer Center Hospital, Tokyo, Japan.
Ayaka TakahashiDepartment of Radiation Oncology, National Cancer Center Hospital, Tokyo, Japan.
Yuri ShimizuDepartment of Radiation Oncology, National Cancer Center Hospital, Tokyo, Japan.
Yuko NakayamaDepartment of Radiation Oncology, National Cancer Center Hospital, Tokyo, Japan.
Tomoyasu KatoDepartment of Gynecologic Oncology, National Cancer Center Hospital, Tokyo, Japan.
Yoshinori ItoDepartment of Radiation Oncology, Showa University Hospital, Tokyo, Japan.
Hiroshi IgakiDepartment of Radiation Oncology, National Cancer Center Hospital, Tokyo, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: Hyaluronate gel has been injected as a spacer into the rectovaginal fossa and vesicouterine fossa during brachytherapy for patients with cervical cancer at our institution. The effect of hyaluronate gel injection (HGI) on dose-volume parameters was investigated in this study. Methods and Materials: Between July 2008 to January 2020, a total of 104 patients (non-HGI group: 52 patients; HGI group: 52 patients) who underwent curative radiation therapy for cervical cancer were selected. The total doses of external beam radiation therapy and brachytherapy for high-risk clinical target volume (CTV Results: Median CTV Conclusions: In cases with HGI, a significant CTV

Identifiers

PMID35647394
PMCPMC9133393

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.