Evidence map›Paper›PMID 35647315›Full record

ArticleEuropean stroke journal2022

Prevalence, risk factors, and long-term outcomes of cerebral ischemia in hospitalized COVID-19 patients - study rationale and protocol of the CORONIS study: A multicentre prospective cohort study.

Theresa J van Lith, Wouter M Sluis, Naomi T Wijers, Frederick Ja Meijer, Karin Kamphuis-van Ulzen, Jeroen de Bresser, Jan Willem Dankbaar, Frederik Ma van den Heuvel, M Louisa Antoni, Catharina M Mulders-Manders and 9 more

Open access · hybridAbstract read
In one paragraph

Article in European stroke journal, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Observational
  2. Article
  3. Relative pandemic severity in Canada and four peer nations during the SARS-CoV-2 pandemic.Canada communicable disease report = Releve des maladies transmissibles au Canada · 2023
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 5 institutions in 1 country.

Theresa J van LithDepartment of Neurology, Donders Center for Medical Neuroscience, Radboud University Medical Center, Nijmegen, The Netherlands.ORCID https://orcid.org/0000-0003-2814-8368
Wouter M SluisDepartment of Neurology and Neurosurgery, Brain Center, University Medical Center Utrecht, Utrecht, The Netherlands.
Naomi T WijersDepartment of Neurology, Leiden University Medical Center, Leiden, The Netherlands.
Frederick Ja MeijerDepartment of Medical Imaging, Radboud University Medical Center, Nijmegen, The Netherlands.ORCID https://orcid.org/0000-0001-5921-639X
Karin Kamphuis-van UlzenDepartment of Medical Imaging, Radboud University Medical Center, Nijmegen, The Netherlands.
Jeroen de BresserDepartment of Radiology, Leiden University Medical Center, Leiden, the Netherlands.
Jan Willem DankbaarDepartment of Radiology and Nuclear Medicine, University Medical Center, Utrecht University, Utrecht, The Netherlands.
Frederik Ma van den HeuvelDepartment of Cardiology, Radboud University Medical Center, Nijmegen, The Netherlands.
M Louisa AntoniDepartment of Cardiology, Heart and Lung Centre, Leiden University Medical Centre, Leiden, The Netherlands.
Catharina M Mulders-MandersDepartment of Internal Medicine, Radboud University Nijmegen Medical Center, Nijmegen, The Netherland.
Quirijn de MastDepartment of Internal Medicine and Radboud Center for Infectious Diseases, Radboud University Medical Center, Nijmegen, The Netherlands.
Frank L van de VeerdonkDepartment of Internal Medicine and Radboud Center for Infectious Diseases, Radboud University Medical Center, Nijmegen, The Netherlands.
Frederikus A KlokDepartment of Medicine - Thrombosis and Hemostasis, Leiden University Medical Centre, Leiden, The Netherlands.ORCID https://orcid.org/0000-0001-9961-0754
Anil M TuladharDepartment of Neurology, Donders Center for Medical Neuroscience, Radboud University Medical Center, Nijmegen, The Netherlands.
Suzanne C CannegieterDepartment of Medicine - Thrombosis and Hemostasis, Leiden University Medical Centre, Leiden, The Netherlands.
Marieke Jh WermerDepartment of Neurology, Leiden University Medical Center, Leiden, The Netherlands.
H Bart van der WorpDepartment of Neurology and Neurosurgery, Brain Center, University Medical Center Utrecht, Utrecht, The Netherlands.ORCID https://orcid.org/0000-0001-9891-2136
Menno V HuismanDepartment of Medicine - Thrombosis and Hemostasis, Leiden University Medical Centre, Leiden, The Netherlands.
Frank-Erik de LeeuwDepartment of Neurology, Donders Center for Medical Neuroscience, Radboud University Medical Center, Nijmegen, The Netherlands.
Radboud University Nijmegen · NLLeiden University Medical Center · NLLeiden University · NLUniversity Medical Center Utrecht · NLUtrecht University · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: COVID-19 is often complicated by thrombo-embolic events including ischemic stroke. The underlying mechanisms of COVID-19-associated ischemic stroke, the incidence and risk factors of silent cerebral ischemia, and the long-term functional outcome in these patients are currently unknown. Patients and methods: CORONavirus and Ischemic Stroke (CORONIS) is a multicentre prospective cohort study investigating the prevalence, risk factors and long-term incidence of (silent) cerebral ischemia, and the long-term functional outcome among patients with COVID-19. We aim to include 200 adult patients hospitalized with COVID-19 without symptomatic ischemic stroke to investigate the prevalence of silent cerebral ischemia compared with 60 (matched) controls with MRI. In addition, we will identify potential risk factors and/or causes of cerebral ischemia in COVID-19 patients with ( Summary: The CORONIS study is designed to add further insight into the prevalence, long-term incidence and risk factors of cerebral ischemia, and the long-term functional outcome in hospitalized adult patients with COVID-19.

Indexed as

COVID-19ischemic strokeSARS-CoV-2silent cerebral ischemia

Identifiers

PMID35647315
PMCPMC9134783
OpenAlexW4226227792

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.