Evidence map›Paper›PMID 35647312›Full record

ArticleEuropean stroke journal2022

Sex differences in outcome after thrombectomy for acute ischemic stroke. A propensity score-matched study.

Ilaria Casetta, Enrico Fainardi, Giovanni Pracucci, Valentina Saia, Fabrizio Sallustio, Valerio da Ros, Sergio Nappini, Patrizia Nencini, Guido Bigliardi, Sergio Vinci and 64 more

Open access · bronzeAbstract read
In one paragraph

Article in European stroke journal, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
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  13. Sex and hypertensive organ damage: stroke.Journal of human hypertension · 2023
    Review
  14. Article
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

74 authors at 20 institutions in 2 countries.

Ilaria CasettaClinical Neurology, University of Ferrara, Ferrara, Italy.ORCID https://orcid.org/0000-0003-4099-8875
Enrico FainardiUniversity of Florence, Florence, Italy.ORCID https://orcid.org/0000-0003-0477-724X
Giovanni PracucciUniversity of Florence, Florence, Italy.
Valentina SaiaHospital Santa Corona Pietra Ligure, Pietra Ligure, Italy.ORCID https://orcid.org/0000-0001-9855-8894
Fabrizio SallustioOspedale dei Castelli-ASL, RM, Ariccia, Italy.
Valerio da RosUniversity of Rome Tor Vergata, RM, Roma, Italy.
Sergio NappiniCareggi University Hospital, Florence, Italy.
Patrizia NenciniCareggi University Hospital, Florence, Italy.
Guido BigliardiUniversity Hospital Modena, Modena, Italy.
Sergio VinciUniversity of Messina, Messina, Italy.
Francesco GrilloUniversity of Messina, Messina, Italy.
Sandra BraccoSanta Maria alle Scotte Hospital, Siena, Italy.
Rossana TassiSanta Maria alle Scotte Hospital, Siena, Italy.ORCID https://orcid.org/0000-0002-5906-8718
Mauro BerguiUniversity of Turin, Torino, Italy.ORCID https://orcid.org/0000-0002-5336-695X
Paolo CerratoAOU Città della Salute, Torino, Italy.
Andrea SalettiAzienda Ospedaliero Universitaria di Ferrara, Ferrara, Italy.
Alessandro De VitoAzienda Ospedaliero Universitaria di Ferrara, Ferrara, Italy.ORCID https://orcid.org/0000-0002-7572-819X
Roberto GasparottiUniversity of Brescia, Brescia, Italy.
Mauro MagoniAzienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia, Brescia, Italy.
Luigi SimonettiOspedale Maggiore, Bologna, Italy.
Andrea ZiniIRCCS Istituto Delle Scienze Neurologiche di Bologna, Bologna, Italy.ORCID https://orcid.org/0000-0003-1486-4507
Maria RuggieroBufalini Hospital, Cesena, Italy.ORCID https://orcid.org/0000-0002-3612-4289
Marco LongoniBufalini Hospital, Cesena, Italy.
Lucio CastellanIRCCS Ospedale Policlinico San Martino, Genova, Italy.
Laura MalfattoIRCCS Ospedale Policlinico San Martino, Genova, Italy.ORCID https://orcid.org/0000-0003-2552-2385
Paola CastelliniOspedale Maggiore di Parma, Parma, Italy.
Mirco CosottiniUniversity of Pisa, Pisa, Italy.
Alessio ComaiBolzano Hospital, Bolzano, Italy.ORCID https://orcid.org/0000-0002-0566-395X
Enrica FranchiniBolzano Hospital, Bolzano, Italy.
Emilio LozuponeHospital Fazzi, Lecce, Italy.ORCID https://orcid.org/0000-0003-3992-9071
Giacomo Della MarcaUniversity Hospital Agostino Gemelli, RM, Roma, Italy.
Edoardo PuglielliASL 4 Teramo, Teramo, Italy.ORCID https://orcid.org/0000-0002-3082-249X
Alfonsina CasalenaASL 4 Teramo, Teramo, Italy.
Claudio BaracchiniUniversity of Padua, Padua, Italy.
Daniele SavioOspedale San Giovanni Bosco, Torino, Italy.
Enrica DucOspedale San Giovanni Bosco, Torino, Italy.
Giuseppe RicciardiAOUI Verona, Verona, Italy.ORCID https://orcid.org/0000-0001-8536-5794
Manuel CappellariAOUI Verona, Verona, Italy.ORCID https://orcid.org/0000-0002-3534-3201
Luigi ChiumaruloUniversity of Bari, Bari, Italy.ORCID https://orcid.org/0000-0001-5790-2353
Marco PetruzzellisUniversity of Bari, Bari, Italy.
Anna CavalliniIRCCS Fondazione C. Mondino, Pavia, Italy.ORCID https://orcid.org/0000-0002-5227-1502
Nicola CavasinOspedale dell'Angelo, Mestre, Italy.ORCID https://orcid.org/0000-0001-6246-3543
Adriana CritelliOspedale dell'Angelo, Mestre, Italy.
Nicola BurdiAO SS. Annunziata, Taranto, Italy.
Giovanni BoeroAO SS. Annunziata, Taranto, Italy.
Andrea GiorgianniASST Sette Laghi, Varese, Italy.ORCID https://orcid.org/0000-0002-4035-3172
Maurizio VersinoUniversity of Insubria, Varese, Italy.ORCID https://orcid.org/0000-0003-1813-9492
Francesco BiraschiUniversity of Rome La Sapienza, RM, Roma, Italy.ORCID https://orcid.org/0000-0001-7660-2401
Ettore NicoliniUniversity of Rome La Sapienza, RM, Roma, Italy.ORCID https://orcid.org/0000-0002-8481-6327
Simone ComelliOspedale Botzu, Cagliari, Italy.
Maurizio MelisOspedale Botzu, Cagliari, Italy.
Riccardo PadolecchiaHospital Santa Corona Pietra Ligure, Pietra Ligure, Italy.
Tiziana TassinariHospital Santa Corona Pietra Ligure, Pietra Ligure, Italy.
Nunzio Paolo NuzziIRCCS Humanitas Research Hospital, Milan, Italy.ORCID https://orcid.org/0000-0003-2615-8554
Simona MarcheselliIRCCS Humanitas Research Hospital, Milan, Italy.
Simona SaccoUniversity of L'Aquila, L' Aquila, Italy.ORCID https://orcid.org/0000-0003-0651-1939
Paolo InvernizziFondazione Poliambulanza, Brescia, Italy.
Ivan GallesioOspedale Casale Monferrato, Alessandria, Italy.
Delfina FerrandiOspedale Casale Monferrato, Alessandria, Italy.
Maria FancelloHospital San Francesco, Nuoro, Italy.
Maria Valeria SaddiHospital San Francesco, Nuoro, Italy.
Monia RussoOspedale Rovigo, Rovigo, Italy.
Aldo PischeddaAOU Sassari, Sassari, Italy.
Antonio BauleAOU Sassari, Sassari, Italy.
Marina ManninoPalermo Hospital, Palermo, Italy.ORCID https://orcid.org/0000-0001-7683-7235
Francesco FlorioFondazione di Religione e di Culto Casa Sollievo della Sofferenza, San Giovanni Rotondo, Foggia, Italy.
Vincenzo InchingoloFondazione di Religione e di Culto Casa Sollievo della Sofferenza, San Giovanni Rotondo, Foggia, Italy.
Maria Elena FlaccoUniversity of Ferrara, Ferrara, Italy.
Daniele RomanoAOU S. Giovanni di Dio Ruggi D'Aragona, Salerno, Italy.
Umberto SilvagniAO Cosenza, Cosenza, Italy.
Domenico InzitariUniversity of Florence, Florence, Italy.
Salvatore MangiaficoCareggi University Hospital, Florence, Italy.ORCID https://orcid.org/0000-0002-5844-3117
Danilo ToniUniversity of Rome La Sapienza, RM, Roma, Italy.
Italian Registry of Endovascular Thrombectomy in Acute Stroke (IRETAS)
Azienda Ospedaliero-Universitaria Careggi · ITOspedale Santa Corona · ITSapienza University of Rome · ITUniversity of Florence · ITATS Sardegna (Italy) · ITAzienda Ospedaliera G. Brotzu · ITAzienda Sanitaria Locale Alessandria · ITAzienda Unità Sanitaria Locale di Ferrara · ITCasa Sollievo della Sofferenza · ITIRCCS Humanitas Research Hospital · ITOspedale dell' Angelo · ITOspedale di Bolzano · ITOspedale “M. Bufalini” di Cesena · ITOspedale Policlinico San Martino · ITOspedale San Giovanni Bosco · ITOspedale Santa Maria alle Scotte · ITOspedale SS. Annunziata · ITUniversity of Bari Aldo Moro · ITUniversity of Ferrara · ITUniversity of Messina · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and purpose: We sought to investigate whether there are gender differences in clinical outcome after stroke due to large vessel occlusion (LVO) after mechanical thrombectomy (EVT) in a large population of real-world patients. Methods: From the Italian Registry of Endovascular Thrombectomy, we extracted clinical and outcome data of patients treated for stroke due to large vessel occlusion. We compared clinical and safety outcomes in men and women who underwent EVT alone or in combination with intravenous thrombolysis (IVT) in the total population and in a Propensity Score matched set. Results: Among 3422 patients included in the study, 1801 (52.6%) were women. Despite older age at onset (mean 72.4 vs 68.7; Conclusions: Subject to the limitations of a non-randomized comparison, women with stroke due to LVO treated with mechanical thrombectomy had a better chance to achieve complete recanalization, and 3-month functional independence than men. The results could be driven by women who underwent combined treatment.

Indexed as

Ischemic strokesexthrombectomy

Identifiers

PMID35647312
PMCPMC9134778
OpenAlexW4226207520

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.