Evidence map›Paper›PMID 35647299›Full record

ArticleOpen life sciences2022

Genetic susceptibility to high myopia in Han Chinese population.

Yufei Li, Yong Zhang, Ping Zhang, Lei Gao, Qingyue Ma, Jin Li, Shengxia Wang, Bing Liu, Xinye Wang, Chao Meng

Open access · goldAbstract read
In one paragraph

Article in Open life sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Association Between Polymorphisms of 4 Common Genes and High Myopia Risk: A Comprehensive Analysis.Medical science monitor : international medical journal of experimental and clinical research · 2026
    Pooled it
  2. Trial
  3. Article
  4. Review
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Yufei LiCollege of Life Sciences, Shandong First Medical University & Shandong Academy of Medical Sciences, Tai'an, 271016, China.
Yong ZhangContinuous Education College, Shandong First Medical University & Shandong Academy of Medical Sciences, Tai'an, 271016, China.
Ping ZhangInfirmary, Shandong First Medical University & Shandong Academy of Medical Sciences, Tai'an, 271016, China.
Lei GaoCollege of Life Sciences, Shandong First Medical University & Shandong Academy of Medical Sciences, Tai'an, 271016, China.
Qingyue MaGraduate School, Shandong First Medical University & Shandong Academy of Medical Sciences, Tai'an, 271016, China.
Jin LiCollege of Pharmacy, Shandong University, Ji'nan, 250100, China.
Shengxia WangOphthalmology Department, Tai'an City Central Hospital, Tai'an, 271000, China.
Bing LiuCollege of Life Sciences, Shandong First Medical University & Shandong Academy of Medical Sciences, Tai'an, 271016, China.
Xinye WangCollege of Basic Medicine, Shandong First Medical University & Shandong Academy of Medical Sciences, Tai'an, 271016, China.
Chao MengCollege of Life Sciences, Shandong First Medical University & Shandong Academy of Medical Sciences, Tai'an, 271016, China.
Shandong First Medical University · CNShandong University · CNTaian City Central Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

High myopia is a common ocular genetic disease in the world. The study sought to investigate the effect of the Insulin-like growth factor-1 (IGF-1) and Matrix metalloproteinase-9 (MMP-9) genes polymorphisms on high myopia in a Han population of China. This study recruited 216 unrelated Han Chinese subjects, including 103 cases with high myopia and 113 controls. Four tagging single nucleotide polymorphisms (SNPs) of

Indexed as

association studyhigh myopiaIGF-1MMP9single nucleotide polymorphism

Identifiers

PMID35647299
PMCPMC9123300
OpenAlexW4285055484

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.