Evidence map›Paper›PMID 35647264›Full record

ArticleInformatics in medicine unlocked2022

Therapeutic capability of five active compounds in typical African medicinal plants against main proteases of SARS-CoV-2 by computational approach.

Oluwasayo Peter Abodunrin, Olayinka Fisayo Onifade, Abayomi Emmanuel Adegboyega

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Informatics in medicine unlocked, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
4.5field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 16 citations in OpenAlex.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Oluwasayo Peter AbodunrinRadiation and Health Physics, Physical Sciences Department, Bells University of Technology, Ota, Nigeria.
Olayinka Fisayo OnifadePhytomedicine, Biochemistry and Bioinformatics, Chemical Sciences Department, Bells University of Technology, Ota, Nigeria.
Abayomi Emmanuel AdegboyegaDepartment of Biochemistry, Faculty of Basic Medical Sciences, University of Jos, Jos, Nigeria.
Bells University of Technology · NGUniversity of Jos · NG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is a pandemic cause of Corona Virus Disease (COVID-19), that has claimed numerous human lives across the globe. Main protease being the active protein of SARS-CoV-2 requires urgent mitigating effect against the spread of the virus. The therapeutic roles of the active compounds present in ten typical African medicinal plants were investigated in this study. Five active compounds

Indexed as

Active compoundsBinding free energyCOVID-19Main proteaseMolecular dockingPharmacophore

Identifiers

PMID35647264
PMCPMC9125996
OpenAlexW4281398676

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.