Evidence map›Paper›PMID 35647262›Full record

ArticleInternational journal of cardiology. Heart & vasculature2022

Early identification of patients with Chagas disease at risk of developing cardiomyopathy using 2-D speckle tracking strain:

Sithu Win, Monica Miranda-Schaeubinger, Ronald Gustavo Durán Saucedo, Paula Carballo Jimenez, Jorge Flores, Brandon Mercado-Saavedra, Lola Camila Telleria, Anne Raafs, Manuela Verastegui, Caryn Bern and 6 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of cardiology. Heart & vasculature, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Serum cytokines and tissue doppler imaging as markers of prognosis of chronic myocarditis due to chagas disease.The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 9 institutions in 6 countries.

Sithu WinUniversity of California San Francisco, San Francisco, CA, USA.
Monica Miranda-SchaeubingerJohns Hopkins University, Bloomberg School of Public Health, Baltimore, MD, USA.
Ronald Gustavo Durán SaucedoUniversidad Católica Boliviana San Pablo, Bolivia.
Paula Carballo JimenezImperial College of London, UK.
Jorge FloresUniversidad Católica Boliviana San Pablo, Bolivia.
Brandon Mercado-SaavedraDepartment of Biochemistry, University of Cambridge, UK.
Lola Camila TelleriaPontificia Universidad Católica de Chile, Santiago, Chile.
Anne RaafsMaastricht University, Cardiovascular Research Institute Maastricht (CARIM), Division of Cardiology, Maastricht, Netherlands.
Manuela VerasteguiUniversidad Peruana Cayetano Heredia, Lima, Peru.
Caryn BernUniversity of California San Francisco, San Francisco, CA, USA.
Freddy TinajerosUniversidad Católica Boliviana San Pablo, Bolivia.
Stephane HeymansMaastricht University, Cardiovascular Research Institute Maastricht (CARIM), Division of Cardiology, Maastricht, Netherlands.
Rachel MarcusMedStar Heart & Vascular Institute, Baltimore, MD, USA.
Robert H GilmanJohns Hopkins University, Bloomberg School of Public Health, Baltimore, MD, USA.
Monica MukherjeeJohns Hopkins University, Division of Cardiology, Baltimore, MD, USA.
Chagas Working Group
Johns Hopkins University · USUniversidad Católica Boliviana San Pablo · BOMaastricht University · NLUniversity of California, San Francisco · USImperial College London · GBMedStar Heart & Vascular Institute · USPontificia Universidad Católica de Chile · CLUniversidad Peruana Cayetano Heredia · PEUniversity of Cambridge · GB

Funding

Predictors of cardiomyopathy progression in a Chagas disease cohort in BoliviaR01AI107028 · NIAID · JOHNS HOPKINS UNIVERSITY · PI GILMAN, ROBERT H · 2014 to 2023
$6.6M
NIAID NIH HHS R01 AI107028
6 · The paper itself

Abstract

Background: Chagas disease is an endemic protozoan disease with high prevalence in Latin America. Of those infected, 20-30% will develop chronic Chagas cardiomyopathy (CCC) however, prediction using existing clinical criteria remains poor. In this study, we investigated the utility of left ventricular (LV) echocardiographic speckle-tracking global longitudinal strain (GLS) for early detection of CCC. Methods and results: 139 asymptomatic Conclusion: Baseline LV GLS in participants with CCC stage A or B was predictive of progression within 1-year and may guide timing of clinical follow-up and promote early detection or treatment.

Indexed as

Chagas cardiomyopathyChagas diseaseEchocardiographyStrain imaging

Identifiers

PMID35647262
PMCPMC9136131
OpenAlexW4281400824

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.