Evidence map›Paper›PMID 35647194›Full record

SynthesisBioMed research international2022

Risk and Prognostic Factors for BRAF

Xiaojing Wei, Xiaodong Wang, Jie Xiong, Chen Li, Yixuan Liao, Yongjun Zhu, Jingxin Mao

Abstract readSystematic Review
In one paragraph

Synthesis in BioMed research international, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
55citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

55 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Development and validation of theAnnals of medicine and surgery (2012) · 2026
    Article
  6. Article
  7. Review
  8. Preoperative Co-Mutation of BRAFCancer medicine · 2026
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Clinical Implications and Application of Molecular Testing in the Diagnosis and Management of Thyroid Nodules in the Chinese Population.Clinical cancer research : an official journal of the American Association for Cancer Research · 2025
    Observational
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Xiaojing WeiChongqing Jiaotong University Hospital, Chongqing 400074, China.
Xiaodong WangChongqing Medical and Pharmaceutical College, Chongqing 400030, China.
Jie XiongDepartment of Pharmacy, Ministry of Education Key Laboratory of Child Development and Disorders, National Clinical Research Center for Child Health and Disorders/Chongqing Key Laboratory of Pediatrics/Children's Hospital of Chongqing Medical University, Chongqing 400014, China.
Chen LiDepartment of Biology, Chemistry, Pharmacy, Free University of Berlin, Berlin 14195, Germany.ORCID https://orcid.org/0000-0002-6895-2759
Yixuan LiaoCollege of Pharmaceutical Sciences, Southwest University, Chongqing 400715, China.
Yongjun ZhuThe Orthopedics department of Ninth People's Hospital of Chongqing, Chongqing 400700, China.ORCID https://orcid.org/0000-0003-1035-1915
Jingxin MaoChongqing Medical and Pharmaceutical College, Chongqing 400030, China.ORCID https://orcid.org/0000-0002-2813-1702

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Over the past ten years, the incidence rate of papillary thyroid carcinoma (PTC) worldwide has been increasing rapidly year by year, with the incidence rate increasing 6% annually. PTC has become the malignant tumor with the highest growth rate in the world that fourteen PTC-related mutant genes have been identified. Whether the BRAF Methods: A total of 9,908 papillary thyroid carcinoma patients with average 74.6% BRAF Results: The following variables were associated with an increased risk of BRAF Conclusion: Our systematic review identified the following significant risk factors of BRAF

Indexed as

Carcinoma, PapillaryThyroid NeoplasmsHumansLymphatic MetastasisMaleMiddle AgedMutationPrognosisProto-Oncogene Proteins B-rafThyroid Cancer, PapillaryBRAF protein, humanProto-Oncogene Proteins B-raf

Identifiers

PMID35647194
PMCPMC9132653

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.