Evidence map›Paper›PMID 35647185›Full record

ArticleBioMed research international2022

Jinlida Granules Reduce Obesity in db/db Mice by Activating Beige Adipocytes.

Hong-Ru Zhou, Tong-Xing Wang, Yuan-Yuan Hao, Yun-Long Hou, Cong Wei, Bing Yao, Xuan Wu, Dan Huang, Hui Zhang, Yi-Ling Wu

Open access · hybridAbstract read
In one paragraph

Article in BioMed research international, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Improving glucose tolerance in obese rats: the role of Jinlida granules ( ) in gut microbiota modulation.Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan · 2026
    Article
  4. Article
  5. Review
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Hong-Ru ZhouHebei Medical University, No. 361 Zhongshan Road, Chang'an District, Shijiazhuang, Hebei Province, China.ORCID https://orcid.org/0000-0002-3902-7206
Tong-Xing WangNational Key Laboratory of Collateral Disease Research and Innovative Chinese Medicine, Shijiazhuang, China.ORCID https://orcid.org/0000-0002-4008-7230
Yuan-Yuan HaoNational Key Laboratory of Collateral Disease Research and Innovative Chinese Medicine, Shijiazhuang, China.ORCID https://orcid.org/0000-0001-8573-5433
Yun-Long HouNational Key Laboratory of Collateral Disease Research and Innovative Chinese Medicine, Shijiazhuang, China.
Cong WeiNational Key Laboratory of Collateral Disease Research and Innovative Chinese Medicine, Shijiazhuang, China.
Bing YaoNational Key Laboratory of Collateral Disease Research and Innovative Chinese Medicine, Shijiazhuang, China.
Xuan WuHebei Medical University, No. 361 Zhongshan Road, Chang'an District, Shijiazhuang, Hebei Province, China.
Dan HuangAffiliated Hospital of Integrated Traditional Chinese and Western Medicine, Nanjing University of Chinese Medicine, Nanjing 210028, China.
Hui ZhangThe First Affiliated Hospital of Henan University of CM, Zhengzhou, China.
Yi-Ling WuNational Key Laboratory of Collateral Disease Research and Innovative Chinese Medicine, Shijiazhuang, China.ORCID https://orcid.org/0000-0002-1882-0184
State Administration of Traditional Chinese Medicine of the People's Republic of China · CNHebei Medical University · CNFirst Affiliated Hospital of Henan University · CNNanjing University of Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recent studies indicate existence of beige adipocytes in adults. Upon activation, beige adipocytes burn energy for thermogenesis and contribute to regulation of energy balance. In this study, we have analyzed whether Jinlida granules (JLD) could activate beige adipocytes. JLD suspended in 0.5% carboxymethyl cellulose (CMC) was gavage fed to db/db mice at a daily dose of 3.8 g/kg. After 10 weeks, body weight, biochemical, and histological analyses were performed. In situ hybridization, immunofluorescence, and western blotting were conducted to test beige adipocyte activation in mice. X9 cells were induced with induction medium and maintenance medium containing 400

Indexed as

Adipocytes, BeigeMicroRNAsAnimalsDrugs, Chinese HerbalMiceMice, Inbred C57BLMice, Inbred StrainsMolecular Docking SimulationObesityUncoupling Protein 1Drugs, Chinese HerbaljinlidaMicroRNAsUncoupling Protein 1

Identifiers

PMID35647185
PMCPMC9135524
OpenAlexW4280558267

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.