Evidence map›Paper›PMID 35647071›Full record

ArticleFrontiers in cardiovascular medicine2022

Cohort Profile: The Shaanxi Blood Donor Cohort in China.

Lei Zhang, Hengxin Li, Shu Su, Erica M Wood, Ting Ma, Yang Sun, Lingxia Guo, Qianke Cheng, Xiaoyun Gu, Wenjie Wu and 5 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cardiovascular medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
3.8field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 8 institutions in 2 countries.

Lei ZhangDepartment of Transfusion Medicine, Shaanxi Provincial People's Hospital, Xi'an, China.
Hengxin LiBlood Quality Management Office, Shaanxi Provincial Blood Center, Xi'an, China.
Shu SuDepartment of Transfusion Medicine, Shaanxi Provincial People's Hospital, Xi'an, China.
Erica M WoodTransfusion Research Unit, School of Public Health and Preventive Medicine, Monash University, Melbourne, VIC, Australia.
Ting MaDepartment of Transfusion Medicine, Shaanxi Provincial People's Hospital, Xi'an, China.
Yang SunData Center, Shaanxi Provincial People's Hospital, Xi'an, China.
Lingxia GuoPlanning Development and Information Office, Health Commission of Shaanxi Province, Xi'an, China.
Qianke ChengDepartment of Information Technological, Shaanxi Health Information Center, Xi'an, China.
Xiaoyun GuDepartment of Information Technological, Shaanxi Health Information Center, Xi'an, China.
Wenjie WuDepartment of Information Technological, Shaanxi Health Information Center, Xi'an, China.
Liqin WangDepartment of Transfusion Medicine, Shaanxi Provincial People's Hospital, Xi'an, China.
Miao DingChina-Australia Joint Research Center for Infectious Diseases, School of Public Health, Xi'an Jiaotong University Health Science Center, Xi'an, China.
Leilei ZhangChina-Australia Joint Research Center for Infectious Diseases, School of Public Health, Xi'an Jiaotong University Health Science Center, Xi'an, China.
Yuan ShenDepartment of Epidemiology and Biostatistics, School of Public Health, Xi'an Jiaotong University Health Science Center, Xi'an, China.
Jiangcun YangDepartment of Transfusion Medicine, Shaanxi Provincial People's Hospital, Xi'an, China.
Shaanxi Provincial People's Hospital · CNXi'an Jiaotong University · CNAlfred Health · AUHealth Commission of Anhui Province · CNMelbourne Sexual Health Centre · AUMonash University · AUShaanxi Blood Center · CNShaanxi Provincial People's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: The Shaanxi Blood Donor Cohort was set up to investigate the impact of blood donation on the health of donors compared with non-blood donors. The specific aims of the study include (1) identifying the geographical and temporal trends of incidence for diseases in both blood donors and non-blood donors; (2) assessing the impact of environmental exposures, lifestyle, body mass index (BMI) and blood type on disease burdens, stratified between blood donors and non-blood donors; and (3) among blood donors, investigating if regular blood donation has a positive impact on donors' health profiles, based on a cohort with a mixed retrospective and prospective study design. Participants: A total of 3.4 million adults, with an equal number and identical demographic characteristics (year of birth, sex and location of residence) of blood donors and non-blood donors, were enrolled on 2012. The one-to-one matching was conducted through a repeated random selection of individuals without any history of blood donation from the Shaanxi Electronic Health Records. The cohort has been so far followed up to the end of 2018, summing to nearly 24 million years of follow-up. The cohort will be followed up prospectively every 3 years until 2030. Findings to Date: Of the 1.7 million blood donors, 418,312 (24.5%) and 332,569 (19.5%) individuals were outpatients and inpatients, accounting for 1,640,483(96.2%) outpatient and 496,061 (29.1%) inpatient visits. Of the same number of non-blood donors, 407,798 (23.9%) and 346,097 (20.3%) individuals were hospital outpatients and inpatients, accounting for 1,655,725 (97.1%) outpatient and 562,337 (33.0%) inpatient visits. The number of outpatient and inpatient visits by non-blood donors was 0.9 and 3.9% higher than those of the blood donors ( Future Plans: We are currently exploring the long term benefits of blood donation on major chronic disease categories and multimorbidities in this large population cohort. The study results are adjusted by the "healthy donor effect." This cohort study will continue until 2030.

Indexed as

blood donationChinacohort profilehealth effectsICD-10

Identifiers

PMID35647071
PMCPMC9130717
OpenAlexW4280568784

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.