Evidence map›Paper›PMID 35646941›Full record

ArticleFrontiers in cell and developmental biology2022

Transcriptomic Analysis Provides Insights to Reveal the

Huan Xu, Guangxiang Tong, Ting Yan, Le Dong, Xiaoxing Yang, Dongyu Dou, Zhipeng Sun, Tianqi Liu, Xianhu Zheng, Jian Yang and 3 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cell and developmental biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
3.1field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 38 citations in OpenAlex.

  1. Pooled it
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  10. The Mutation ofInternational journal of molecular sciences · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 2 countries.

Huan XuHeilongjiang River Fisheries Research Institute of Chinese Academy of Fishery Sciences, Harbin, China.
Guangxiang TongHeilongjiang River Fisheries Research Institute of Chinese Academy of Fishery Sciences, Harbin, China.
Ting YanHeilongjiang River Fisheries Research Institute of Chinese Academy of Fishery Sciences, Harbin, China.
Le DongHeilongjiang River Fisheries Research Institute of Chinese Academy of Fishery Sciences, Harbin, China.
Xiaoxing YangHeilongjiang River Fisheries Research Institute of Chinese Academy of Fishery Sciences, Harbin, China.
Dongyu DouHeilongjiang River Fisheries Research Institute of Chinese Academy of Fishery Sciences, Harbin, China.
Zhipeng SunHeilongjiang River Fisheries Research Institute of Chinese Academy of Fishery Sciences, Harbin, China.
Tianqi LiuHeilongjiang River Fisheries Research Institute of Chinese Academy of Fishery Sciences, Harbin, China.
Xianhu ZhengHeilongjiang River Fisheries Research Institute of Chinese Academy of Fishery Sciences, Harbin, China.
Jian YangInstitute of Mariculture Breeding and Seed Industry, Zhejiang Wanli University, Ningbo, China.
Xiaowen SunHeilongjiang River Fisheries Research Institute of Chinese Academy of Fishery Sciences, Harbin, China.
Yi ZhouStem Cell Program of Boston Children's Hospital, Division of Hematology/Oncology, Boston Children's Hospital and Dana Farber Cancer Institute, Harvard Medical School, Boston, MA, United States.
Youyi KuangHeilongjiang River Fisheries Research Institute of Chinese Academy of Fishery Sciences, Harbin, China.
Chinese Academy of Fishery Sciences · CNMinistry of Agriculture and Rural Affairs · CNDana-Farber Cancer Institute · USShanghai Ocean University · CNZhejiang Wanli University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Intermuscular bones (IBs) are small, hard-boned spicules located in the muscle tissue that mainly exist in the myosepta of lower teleosts, which hurt the edibleness and economic value of fish. The study of the development of IBs is very important for freshwater aquaculture fish, but the molecular mechanism of its formation and the key regulatory genes remain unclear. In this study, we first constructed two types of zebrafish mutants (the mutants losing IBs and the mutants with partial deletion of IBs) by knocking out

Indexed as

BMP6bone developmentintermuscular bonesSIK1zebrafish

Identifiers

PMID35646941
PMCPMC9135397
OpenAlexW4280529554

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.