Evidence map›Paper›PMID 35646829›Full record

ReviewFrontiers in chemistry2022

Direct Modification of Extracellular Vesicles and Its Applications for Cancer Therapy: A Mini-Review.

Wenbin Nan, Chao Zhang, Hao Wang, Hongli Chen, Shenglu Ji

Open access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Frontiers in chemistry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 25 citations in OpenAlex.

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  13. Extracellular Vesicles: A New Star for Gene Drug Delivery.International journal of nanomedicine · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Wenbin NanCollege of Life Science and Technology, Nano Biomedical Materials Research Center, Xinxiang Medical University, Xinxiang, China.
Chao ZhangCollege of Life Science and Technology, Nano Biomedical Materials Research Center, Xinxiang Medical University, Xinxiang, China.
Hao WangCollege of Life Science and Technology, Nano Biomedical Materials Research Center, Xinxiang Medical University, Xinxiang, China.
Hongli ChenCollege of Life Science and Technology, Nano Biomedical Materials Research Center, Xinxiang Medical University, Xinxiang, China.
Shenglu JiCollege of Life Science and Technology, Nano Biomedical Materials Research Center, Xinxiang Medical University, Xinxiang, China.
Xinxiang Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Extracellular vesicles (EVs) are a class of lipid membrane-bound vesicles released by various cells and mediate cell-to-cell communication. By reason of their high physiochemical stability and biocompatibility, EVs are considered as novel drug delivery system. An increasing number of studies have indicated that EVs can be modified to enhance their loading efficiency, targeting ability and therapeutic capabilities for cancer therapy. Compared with the tedious process of gene engineering approaches, direct modification of EVs is easier, faster and versatile. This mini review will summarize the prevailing approaches for direct modification of EVs. Additionally, the potential applications of modified EVs in cancer therapy are also discussed, which will help readers gain a better understanding of the technologies and applications in this field.

Indexed as

cancer therapydrug deliveryextracellular vesiclesmodificationnanomedicine

Identifiers

PMID35646829
PMCPMC9130553
OpenAlexW4280548322

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.