Evidence map›Paper›PMID 35646816›Full record

ArticleFrontiers in chemistry2022

Co-Delivery of Doxycycline and Hydroxychloroquine Using CdTe-Labeled Solid Lipid Nanoparticles for Treatment of Acute and Chronic Brucellosis.

Seyed Mostafa Hosseini, Abbas Farmany, Mohammad Yousef Alikhani, Mohammad Taheri, Sara Soleimani Asl, Saeed Alamian, Mohammad Reza Arabestani

Open access · goldAbstract read
In one paragraph

Article in Frontiers in chemistry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
5.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.

  1. Pooled it
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  4. [Analysis of factors affecting fibrosis reversal in patients with metabolic associated steatohepatitis based on magnetic resonance elastography].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Seyed Mostafa HosseiniDepartment of Microbiology, Faculty of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran.
Abbas FarmanyDental Research Center, School of Dentistry, Hamadan University of Medical Sciences, Hamadan, Iran.
Mohammad Yousef AlikhaniDepartment of Microbiology, Faculty of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran.
Mohammad TaheriDepartment of Microbiology, Faculty of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran.
Sara Soleimani AslDepartment of Anatomical Sciences, Faculty of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran.
Saeed AlamianRazi Vaccine and Serum Research Institute, Agricultural Research, Education and Extension Organization (AREEO), Karaj, Iran.
Mohammad Reza ArabestaniDepartment of Microbiology, Faculty of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran.
Hamedan University of Medical Sciences · IRRazi Vaccine and Serum Research Institute · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Brucellosis is a systemic disease in both acute and chronic forms which can affect any organ or tissue in the body. One of the biggest issues in treating this disease is its relapse. In this study, a complete treatment of brucellosis was evaluated using enhanced performance of doxycycline and hydroxychloroquine drugs by using solid lipid nanoparticles (SLN) conjugated cadmium-telluride quantum dots. The double emulsion method was used to prepare SLN and cadmium-telluride quantum dots. The physicochemical properties of NPs were determined. The effect of nanoparticle-loaded antibiotics against

Indexed as

Brucella melitensisbrucellosisdoxycyclinehydroxychloroquinesolid lipid nanoparticles

Identifiers

PMID35646816
PMCPMC9130827
OpenAlexW4280521883

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.