Evidence map›Paper›PMID 35646811›Full record

ReviewFrontiers in chemistry2022

Metal Graphitic Nanocapsules for Theranostics in Harsh Conditions.

Yanxia Yang, Shengkai Li, Hongxiu Bu, Xin Xia, Long Chen, Yiting Xu, Zhuo Chen

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Frontiers in chemistry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Yanxia YangAptamer Engineering Center of Hunan Province, Molecular Science and Biomedicine Laboratory (MBL), State Key Laboratory of Chemo/Bio-Sensing and Chemometrics, Hunan Provincial Key Laboratory of Biomacromolecular Chemical Biology, College of Chemistry and Chemical Engineering, Hunan University, Changsha, China.
Shengkai LiAptamer Engineering Center of Hunan Province, Molecular Science and Biomedicine Laboratory (MBL), State Key Laboratory of Chemo/Bio-Sensing and Chemometrics, Hunan Provincial Key Laboratory of Biomacromolecular Chemical Biology, College of Chemistry and Chemical Engineering, Hunan University, Changsha, China.
Hongxiu BuAptamer Engineering Center of Hunan Province, Molecular Science and Biomedicine Laboratory (MBL), State Key Laboratory of Chemo/Bio-Sensing and Chemometrics, Hunan Provincial Key Laboratory of Biomacromolecular Chemical Biology, College of Chemistry and Chemical Engineering, Hunan University, Changsha, China.
Xin XiaAptamer Engineering Center of Hunan Province, Molecular Science and Biomedicine Laboratory (MBL), State Key Laboratory of Chemo/Bio-Sensing and Chemometrics, Hunan Provincial Key Laboratory of Biomacromolecular Chemical Biology, College of Chemistry and Chemical Engineering, Hunan University, Changsha, China.
Long ChenFaculty of Science and Technology, University of Macau, Macau, China.
Yiting XuKey Laboratory of Theoretical Organic Chemistry and Function Molecule, Ministry of Education, School of Chemistry and Chemical Engineering, Hunan University of Science and Technology, Xiangtan, China.
Zhuo ChenAptamer Engineering Center of Hunan Province, Molecular Science and Biomedicine Laboratory (MBL), State Key Laboratory of Chemo/Bio-Sensing and Chemometrics, Hunan Provincial Key Laboratory of Biomacromolecular Chemical Biology, College of Chemistry and Chemical Engineering, Hunan University, Changsha, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Metal nanoparticles (NPs) with superior physicochemical properties and biocompatibility have shown great potential in theranostics. However, metal NPs show poor stability in some harsh conditions such as strong acid, oxidation, corrosion and high-temperature conditions, which limits their extensive bioapplications. To address such issue, a variety of superstable metal graphitic nanocapsules with the metal cores confined in the nanospace of few-layer graphitic shell have been developed for biodetection and therapy in harsh conditions. In this mini-review, we summarize the recent advances in metal graphitic nanocapsules for bioapplications in harsh conditions. Firstly, their theranostic performance in non-intrinsic physiological harsh environment, including oxidation, corrosion and high-temperature conditions, is systematically discussed. Then, we highlight their theranostic performance in the harsh stomach condition that is strong acidic and pepsin-rich. It is expected that this review will offer inspiration to facilitate the exploitation of novel theranostic agents that are stable in harsh conditions.

Indexed as

gastric environmentharsh conditionmetal graphitic nanocapsulesstabilitytheranostics

Identifiers

PMID35646811
PMCPMC9136136

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.