Evidence map›Paper›PMID 35646747›Full record

ReviewFrontiers in cellular and infection microbiology2022

Pneumococcal Surface Proteins as Virulence Factors, Immunogens, and Conserved Vaccine Targets.

Javid Aceil, Fikri Y Avci

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in cellular and infection microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
6.1field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 45 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Identification ofJournal of proteome research · 2025
    Article
  11. Human vaccines & immunotherapeutics · 2025
    Review
  12. Article
  13. Review
  14. Article
  15. Novel processes to obtain pneumococcal surface proteins for vaccines.Applied microbiology and biotechnology · 2025
    Review
  16. Review
  17. Article
  18. Article
  19. State of pneumococcal vaccine immunity.Human vaccines & immunotherapeutics · 2024
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Javid AceilDepartment of Biochemistry and Molecular Biology, Center for Molecular Medicine, The University of Georgia, Athens, GA, United States.
Fikri Y AvciDepartment of Biochemistry and Molecular Biology, Center for Molecular Medicine, The University of Georgia, Athens, GA, United States.
University of Georgia · US

Funding

Molecular Mechanisms for Carbohydrate Presentation to CD4+ T cells by MHCII PathwayR01AI123383 · NIAID · UNIVERSITY OF GEORGIA · PI Fikri Y Avci · 2016 to 2026
$4.2M
Glycopeptide-specific helper T cells eliciting protective humoral immunity against HIV - ResubmissionR01AI152766 · NIAID · UNIVERSITY OF GEORGIA · PI Fikri Y Avci · 2021 to 2026
$2.6M
Pn3Pase as an Effective Enzyme Therapeutic for Streptococcus Pneumoniae type 3 InfectionR41AI157287 · NIAID · PNEUMOTACTIX, LLC · PI AVCI, FIKRI Y · 2021 to 2022
$599k
NIAID NIH HHS R01 AI123383NIAID NIH HHS R01 AI152766NIAID NIH HHS R41 AI157287
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Membrane ProteinsStreptococcus pneumoniaeVirulence FactorsHumansPneumococcal InfectionsPneumococcal VaccinesMembrane ProteinsPneumococcal VaccinesVirulence FactorsCbpAconjugate vaccinePhtD pneumococcal histidine triad protein Dpneumococcal protein vaccinepneumolysin (PLY)PspAPsrPStreptoccoccus pneumoniae

Identifiers

PMID35646747
PMCPMC9133333
OpenAlexW4280509542

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.