ArticleFrontiers in cellular and infection microbiology2022
Subgingival Microbiome in Pregnancy and a Potential Relationship to Early Term Birth.
Article in Frontiers in cellular and infection microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed.
- Characterizing the supragingival microbiome of healthy pregnant women.Frontiers in cellular and infection microbiology · 2022Trial
- Association Between E-Cigarette Use (Vaping) and Oral Health in Adolescents and Young Adults: A Systematic Review.Journal of clinical medicine · 2026Review
- Neighborhood deadwood and yard rewilding modulate commensal microbiomes and inflammatory signals among urbanites.Microbiome · 2026Article
- [Design and evaluation of an oral health booklet during pregnancy].Atencion primaria · 2026Observational
- The role of oral dysbiosis in pregnancy complications: a systematic review and meta-analysis of preterm birth.Journal of oral microbiology · 2026Review
- The oral microbiome in relation to systemic maternal conditions and pregnancy complications: a systematic review and meta-analysis.Journal of oral microbiology · 2026Review
- The oral - X axis: from periodontal dysbiosis to systemic disease.Frontiers in immunology · 2026Review
- Clinical Characteristics and Antimicrobial Susceptibility ofInfection and drug resistance · 2026Article
- The impact of vaping behavior on functional changes within the subgingival microbiome.Scientific reports · 2025Article
- Dynamic changes in the pregnancy microbiome and their role in preterm birth.Frontiers in cellular and infection microbiology · 2025Review
- The Safety of Probiotics Intended for Use in Pregnant and Lactating Women: From a Desirable to a Required Task.Foods (Basel, Switzerland) · 2024Review
- Periodontitis: etiology, conventional treatments, and emerging bacteriophage and predatory bacteria therapies.Frontiers in microbiology · 2024Review
- Interleukin 1 beta and its association with the periodontal health of pregnant women.Journal of Taibah University Medical Sciences · 2023Article
- Predicting preterm birth using machine learning techniques in oral microbiome.Scientific reports · 2023Article
- Extracellular Vesicles ofLife (Basel, Switzerland) · 2023Article
- [Developments in Research on the Relationship BetweenSichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition · 2023Review
- Oral microbiome and preterm birth.Frontiers in medicine · 2023Article
- Effects of an Ozonated Water Irrigator on the Plaque Index and Bleeding Index of Pregnant Women.Journal of clinical medicine · 2022Article
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
Background: Periodontal disease in pregnancy is considered a risk factor for adverse birth outcomes. Periodontal disease has a microbial etiology, however, the current state of knowledge about the subgingival microbiome in pregnancy is not well understood. Objective: To characterize the structure and diversity of the subgingival microbiome in early and late pregnancy and explore relationships between the subgingival microbiome and preterm birth among pregnant Black women. Methods: This longitudinal descriptive study used 16S rRNA sequencing to profile the subgingival microbiome of 59 Black women and describe microbial ecology using alpha and beta diversity metrics. We also compared microbiome features across early (8-14 weeks) and late (24-30 weeks) gestation overall and according to gestational age at birth outcomes (spontaneous preterm, spontaneous early term, full term). Results: In this sample of Black pregnant women, the top twenty bacterial taxa represented in the subgingival microbiome included a spectrum representative of various stages of biofilm progression leading to periodontal disease, including known periopathogens Conclusions: Although the composition of the subgingival microbiome is shifted toward complexes associated with periodontal disease, the diversity of the microbiome remains stable throughout pregnancy. Several taxa were identified as being associated with spontaneous early term birth. Two, in particular, are promising targets of further investigation. Depletion of the oral commensal
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