ArticleFrontiers in cellular and infection microbiology2022
Uterine Fibroid Patients Reveal Alterations in the Gut Microbiome.
Article in Frontiers in cellular and infection microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 2 of them syntheses that pooled it.
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Who cites it
16 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Alterations in gut and genital microbiota associated with gynecological diseases: a systematic review and meta-analysis.Reproductive biology and endocrinology : RB&E · 2024Pooled it
- The role of microbiota in the pathophysiology of uterine fibroids - a systematic review.Frontiers in cellular and infection microbiology · 2023Pooled it
- Myometrial Microbiome in Uterine Fibroids: Functional Dysbiosis Versus Limited Taxonomic Change.Biology · 2026Article
- Gut Dysbiosis in Selected Gynecological Diseases Associated with Female Infertility: A Scoping Review.Journal of clinical medicine · 2026Review
- Multi-Omics Analysis Reveals the Gut-Mediated Mechanism Underlying the Seasonal Non-Laying Phenotype in Zhedong White Geese (Animals : an open access journal from MDPI · 2026Article
- A Dive into the Invisible: The Vaginal and Endometrial Microbiota in Gynecologic and Obstetric Disorders: A Narrative Review.Life (Basel, Switzerland) · 2026Review
- Article
- Associations between dietary inflammatory index with menopause and hysterectomy: findings from a national health and nutrition examination survey.BMC public health · 2025Article
- Complicated Sigmoid Diverticulitis Mimicking Pelvic Pain in a Patient With Giant Uterine Fibroids: A Case Report.Cureus · 2025Article
- Article
- Causal Link between Gut Microbiota and Infertility: A Two-sample Bidirectional Mendelian Randomization Study.Current medical science · 2024Article
- Psychological distress and uterine fibroids: a bidirectional two-sample mendelian randomization study.BMC women's health · 2024Article
- Effect of stress urinary incontinence on vaginal microbial communities.BMC microbiology · 2024Article
- Causal relationship between gut microbiota and gynecological tumor: a two-sample Mendelian randomization study.Frontiers in microbiology · 2024Article
- Alterations in vaginal microbiota in uterine fibroids patients with ultrasound-guided high-intensity focused ultrasound ablation.Frontiers in microbiology · 2023Article
- Characteristics of the Gut Microbiota in Japanese Patients with Premenstrual Syndrome.International journal of women's health · 2022Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The gut microbiota is associated with reproductive disorders in multiple ways. This research investigated possible differences in gut microbiome compositions between patients with uterine fibroids (UFs) and healthy control subjects in order to further provide new insight into its etiology. Stool samples were collected from 85 participants, including 42 UF patients (case group) and 43 control subjects (control group). The gut microbiota was examined with 16S rRNA quantitative arrays and bioinformatics analysis. The α-diversity in patients with UFs was significantly lower than that of healthy controls and negatively correlated with the number of tumorigeneses. The microbial composition of the UF patients deviated from the cluster of healthy controls. Stool samples from patients with UFs exhibited significant alterations in terms of multiple bacterial phyla, such as Firmicutes, Proteobacteria, Actinobacteria, and Verrucomicrobia. In differential abundance analysis, some bacteria species were shown to be downregulated (
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